Review Article

Pharmaceutical Values of Calycosin: One Type of Flavonoid Isolated from Astragalus

Table 2

Antioxidative functions.

BiomarkersModelReference

Enhance glutathione peroxidase, catalase, and superoxide dismutase enzymatic activitiesH9C2 cells and male Kunming miceZhai et al. [36]
Reduced H2O2-induced cell apoptosis rateH9C2Chen et al. [37]; Liu et al. [38]
Downregulation of cytokine levels and IL33/ST2 mRNA levelType 2 diabetes mellitus rat modelWang & Zhao [39]; EIsherbiny et al. [40]
Stimulating Nrf2 expression and SOD levelsIntracerebral hemorrhage mouseMa et al. [41]; Chen et al. [42]
Prolong lifespan and stimulate SOD levelsC. elegansLu et al. [43]