Evidence-Based Complementary and Alternative Medicine

Research Article

Combination of HPLC-Q-TOF-MS/MS, Network Pharmacology, and Molecular Docking to Reveal the Mechanism of Apple Pollen in the Treatment of Type 2 Diabetes Mellitus

Table 1

Identification of chemical compositions in Qinguan pollen by HPLC-QTOF-MS/MS.
No.tR/minm/zMSFormulaMS2Component
14.24331.0815330.0774 (M-H)-C17H15O7285, 251, 199, 145Malvidin
24.44182.0784181.0744 (M-H)-C6H14O6182, 168, 146, 131D-(-)-Mannitol
35.05200.0619199.033 (M-H)-C8H12N2O2S199, 187, 179, 146, 135N,N-Dimethyl-n′-phenylsulfamide
46.90196.0581195.0508 (M-H)-C6H12O7195, 179, 146, 129Gluconic acid
57.04134.0214133.0141 (M-H)-C4H6O5133, 127, 71, 62Malic acid
67.56226.1317225.0160 (M-H)-C11H18N2O225, 209, 197, 181, 160Amobarbital
718.79280.0456279.0383 (M-H)-C18H32O2279, 252, 233, 201, 180Linoleic acid
819.55162.0528161.482 (M-H)-C6H10O5161, 146, 130, 96, 793-Hydroxy-3-methylglutaric acid
921.57165.065164.0743 (M-H)-C6HN5O164, 146, 129, 116, 967-Methylguanine
1022.15191.0582189.8607 (M-H)-C10H9NO3189, 174, 164, 160, 1295-Hydroxyindoleacetic acid
1125.42204.0898203.0854 (M-H)-C11H12N2O2203, 197, 146, 129, 113, 100, 92L-Tryptophan
1229.31326.1001325.0924 (M-H)-C15H18O8325, 292, 258, 145, 117Coumarinic acid-beta-D-glucoside
1330.83354.0945353.0872 (M-H)-C16H18O9353, 322, 209, 191, 173Chlorogenic acid
1435.30304.2013303.1079 (M+H)-C20H32O2305, 213, 191, 173, 169Arachidonic acid
1540.95164.0473163.0395 (M-H)C9H8O3163154, 145, 119, 104, 93m-Coumaric acid
1642.67166.0627165.0554 (M-H)-C9H10O3165, 146, 129, 117, 101DL-3-Phenyllactic acid
1743.72640.1638639.1565 (M-H)-C28H32O17639, 514, 503, 459, 399314Isorhamnetin-3-glucoside-4′-glucoside
1853.60436.1362435.1289 (M-H)-C21H24O10435, 379, 273, 229, 179Phloridzin
1953.70478.1105477.1032 (M-H)-C22H22O12477, 435, 395, 357, 299Isorhamnetin-3-O-glucosie
2055.05508.121507.1137 (M-H)-C23H24O13507, 387, 359, 329, 258Syringetin-3-O-galactoside
2168.70316.057315.0505 (M-H)-C16H12O7255, 227, 193, 165, 136Rhamnetin