Combination of HPLC-Q-TOF-MS/MS, Network Pharmacology, and Molecular Docking to Reveal the Mechanism of Apple Pollen in the Treatment of Type 2 Diabetes Mellitus

Table 3

Absorption parameters of the components.

No.	Compounds	Pharmacokinetics	Druglikeness (yes ≥ 2)	Results
		GI absorption	Lipinski/Veber/Ghose/Egan/Muegge
1	Malvidin	High	√	√
2	D-(-)-Mannitol	Low	√	×
3	N,N-Dimethyl-n′-phenylsulfamide	High	√	√
4	Gluconic acid	Low	√	×
5	Malic acid	High	√	√
6	Amobarbital	High	√	√
7	Linoleic acid	High	√	√
8	3-Hydroxy-3-methylglutaric acid	High	√	√
9	7-Methylguanine	High	√	√
10	5-Hydroxyindoleacetic acid	High	√	√
11	L-Tryptophan	High	√	√
12	Coumarinic acid-beta-D-glucoside	Low	×	×
13	Chlorogenic acid	Low	×	×
14	Arachidonic acid	High	√	√
15	DL-3-Phenyllactic acid	High	√	√
16	Isorhamnetin-3-glucoside-4′-glucoside	—	—	—
17	Phloridzin	Low	×	×
18	Isorhamnetin-3-O-glucoside	High	√	√
19	Syringetin-3-O-galactoside	Low	×	×
20	Rhamnetin	High	√	√
21	Glutaric acid	High	√	√
22	Dulcitol	Low	√	×
23	m-Coumaric acid	High	√	√
24	Isorhamnetin-3,4′-diglucoside	—	—	—
25	Isorhamnetin-3-galactoside-6′-rhamnoside	—	—	—
26	Quercitrin	High	√	√
27	Kaempferol-3-O-alpha-L-arabinoside	High	√	√
28	Kaempferol	High	√	√