Herbal Medicines for the Treatment of Chronic Obstructive Airway Diseases (Asthma or Chronic Obstructive Pulmonary Disease): A Prospective Observational Study
Table 8
Biomarkers before and after herbal medicine treatments.
Total (n = 22)
Asthma (n = 12)
COPD (n = 10)
TNF-α
Baseline
8.89 (−3.14, 20.92)
12.32 (−8.14, 32.79)
3.55 (−0.90, 8.00)
Week 12
2.56 (1.50, 3.62)
1.79 (0.89, 2.69)
3.75 (1.67, 5.83)
value
0.2751
0.2649
0.8899
IL-4
Baseline
4.59 (4.11, 5.07)
4.66 (4.06, 5.25)
4.48 (3.48, 5.49)
Week 12
5.09 (4.30, 5.88)
4.74 (3.88, 5.59)
5.64 (4.26, 7.03)
value
0.2323
0.8526
0.1290
IL-5
Baseline
0.99 (0.62, 1.36)
1.06 (0.46, 1.67)
0.88 (0.48, 1.27)
Week 12
1.53 (0.84, 2.22)
1.23 (0.30, 2.16)
2.00 (0.95, 3.04)
value
0.2075
0.7700
0.0675
IL-6
Baseline
1.26 (-0.67, 3.20)
1.63 (-1.68, 4.94)
0.69 (-0.13, 1.51)
Week 12
0.38 (0.18, 0.59)
0.31 (0.07, 0.55)
0.50 (0.11, 0.89)
value
0.3524
0.3957
0.4763
IL-13
Baseline
27.77 (17.45, 38.10)
27.96 (17.88, 38.03)
27.48 (2.30, 52.66)
Week 12
15.13 (6.03, 24.24)
15.61 (1.16, 30.05)
14.40 (5.30, 23.50)
value
0.0411
0.1182
0.2267
CRP
Baseline
0.203 (0.069, 0.337)
0.098 (0.036, 0.160)
0.350 (0.031, 0.669)
Week 12
0.387 (0.070, 0.705)
0.218 (0.035, 0.442)
0.625 (0.000, 1.320)
value
0.1768
0.3129
0.3455
Fibrinogen
Baseline
394.3 (328.8, 459.7)
353.6 (287.2, 419.9)
451.2 (315.2, 587.2)
Week 12
367.2 (324.3, 410.1)
336.4 (295.5, 377.3)
410.3 (332.5, 488.1)
value
0.2901
0.5115
0.4103
IgE
Baseline
173.0 (74.6, 271.3)
220.7 (56.0, 385.3)
106.2 (25.5, 186.8)
Week 12
158.6 (77.1, 240.0)
195.1 (64.0, 326.2)
107.4 (44.8, 170.3)
value
0.1281
0.0541
0.9186
Data are presented as mean (95% CI). value by paired t-test ().
