Research Article

Systematic Understanding of Mechanism of Danggui Shaoyao San against Ischemic Stroke Using a Network Pharmacology Approach

Table 5

Binding energy between the key ingredients and target proteins.

NO.Receptor proteinMolecule IDLigand componentBinding energy (kcal·mol-1)

1MAPK1MOL00002012-Senecioyl-2E, 8E, 10E-atractylentriol−5.99
2MAPK1MOL000287Eburicoic acid−8.64
3MAPK1MOL00191011alpha,12alpha-epoxy-3beta-23-Dihydroxy-30-nor-olean-20-en-28,12beta-olide−9.32
4PIK3R1MOL00002012-Senecioyl-2E, 8E, 10E-atractylentriol−6.66
5PIK3R1MOL000287Eburicoic acid−9.24
6PIK3R1MOL00191011alpha,12alpha-epoxy-3beta-23-Dihydroxy-30-nor-olean-20-en-28,12beta-olide−10.18
7SRCMOL00002012-Senecioyl-2E, 8E, 10E-atractylentriol−7.57
8SRCMOL000287Eburicoic acid−9.42
9SRCMOL00191011alpha,12alpha-epoxy-3beta-23-Dihydroxy-30-nor-olean-20-en-28,12beta-olide−9