Evaluation of Antidiabetic and Antihyperlipidemic Activity of 80% Methanolic Extract of the Root of Solanum incanum Linnaeus (Solanaceae) in Mice

Table 3

Hypoglycemic activity of hydro-methanolic root extract of Solanum incanum L. in normoglycemic mice.

Group	Blood glucose level (mg/dl)
	Baseline	1 h	2 h	4 h	6 h
DW10	123.70 ± 1.18	121.88 ± 1.37	122.43 ± 0.86	123.43 ± 0.69^d3	122.77 ± 1.00^c3d3
SIRE100	124.53 ± 1.10	122.04 ± 0.91	123.65 ± 0.80	123.66 ± 0.85^d3	122.80 ± 0.78^c3d3
SIRE200	125.12 ± 0.74	123.99 ± 0.88	123.32 ± 0.66	123.64 ± 0.66^d3	112.16 ± 0.86^a3b3d1
SIRE 400	124.70 ± 0.65	123.50 ± 0.72	123.40 ± 0.60	112.28 ± 1.04^a3b3c3	108.24 ± 0.60^a3b3c1
GLC5	124.66 ± 0.64	119.99 ± 0.78	108.40 ± 1.00^a3b2c2d1	100.16 ± 0.99^a3b3c3d1	95.05 ± 0.87^a3b3c3d2

Results are expressed as mean ± SEM (n = 6) and analyzed by one-way ANOVA followed by Tukey’s post hoc test. ^a Compared with the negative control,^b compared with SIRE 100 mg/kg,^c compared with SIRE 200 mg/kg, and ^d compared with SIRE 400 mg/kg.¹,², and ³. SIRE = Solanum incanum root extract, DW = distilled water, and GLC = glibenclamide.