Evaluation of Antidiabetic and Antihyperlipidemic Activity of 80% Methanolic Extract of the Root of Solanum incanum Linnaeus (Solanaceae) in Mice

Table 4

Effect of hydro-methanolic extract of the root of Solanum incanum L. in oral glucose-loaded mice.

Group	Blood glucose level (mg/dl)
	Baseline	30 min	60 min	120 min
DW10	126.35 ± 0.74	185.17 ± 2.10	185.15 ± 2.16^c1d3	182.53 ± 1.58^c2d3
SIRE100	127.26 ± 1.24	183.00 ± 1.90	178.21 ± 2.40^d3	177.13 ± 1.53^d3
SIRE200	127.28 ± 1.05	184.78 ± 1.46	176.34 ± 1.84^a1	174.77 ± 1.36^a2d2
SIRE 400	126.13 ± 1.31	185.83 ± 0.82	172.14 ± 0.80^a3	165.14 ± 1.39^a3b3c2
GLC5	127.08 ± 0.80	183.72 ± 1.17	147.62 ± 1.50^a3b3c3d2	144.65 ± 1.32^a3b3c2d1

Results are expressed as mean ± SEM (n = 6) and analyzed by one-way ANOVA followed by Tukey’s post hoc test. ^a Compared with negative control, ^b compared with SIRE 100 mg/kg, ^c compared with SIRE 200 mg/kg, and ^d compared with SIRE 400 mg/kg. ¹, ², and ³. SIRE = Solanum incanum root extract, DW = distilled water, and GLC = glibenclamide.