Evaluation of Antidiabetic and Antihyperlipidemic Activity of 80% Methanolic Extract of the Root of Solanum incanum Linnaeus (Solanaceae) in Mice

Table 6

Effect of hydro-methanolic extract of the root of Solanum incanum L. on the body weight of STZ-induced diabetic mice.

Group	Body weight (g)
	Before induction of DM	Baseline	7^th day of treatment	14^th day of treatment
DC	31.11 ± 0.80	27.34 ± 0.93^n2	26.66 ± 1.03^n3	25.69 ± 1.10^n3
SIRE100	30.94 ± 0.85	26.78 ± 0.91^n2	27.79 ± 0.78^n2	27.91 ± 0.56^n2
SIRE200	30.84 ± 1.21	27.43 ± 1.11^n2	28.22 ± 0.72^n2	31.27 ± 0.53^a1
SIRE 400	33.14 ± 0.83	28.14 ± 0.44^n2	31.62 ± 0.65^a2	32.59 ± 1.41^a2
GLC5	33.83 ± 0.63	28.45 ± 1.04^n2	32.34 ± 0.97^a3	33.23 ± 1.11^a3
NC	31.13 ± 0.58	32.21 ± 0.79^a2	33.50 ± 1.15^a3	34.37 ± 1.35^a3

Results are expressed as mean ± SEM (n = 6) and analyzed by one-way ANOVA followed by Tukey’s post hoc test. ^a Compared with the diabetic control, and ⁿ compared with the normal control. ¹, ², and ³. SIRE = Solanum incanum root extract, DC = diabetic control, NC = normal control, and GLC = glibenclamide.