Research Article

Effects of Chinese Medicine on the Survival of AIDS Patients Administered Second-Line ART in Rural Areas of China: A Retrospective Cohort Study Based on Real-World Data

Table 1

Comparisons of baseline data of the CM + ART and ART groups before and after PSM.

VariablesBefore PSMAfter PSM
ART (n = 3,325)CM + ART (n = 855) valueART (n = 1,699)CM + ART (n = 855) value

Gender0.4760.945
Female1545 (46.5%)385 (45.0%)930 (54.7%)470 (55.0%)
Male1780 (53.5%)470 (55.0%)769 (45.3%)385 (45.0%)

Age (years)0.0020.936
18–40591 (17.8%)110 (12.9%)210 (12.4%)110 (12.9%)
40–501547 (46.5%)412 (48.2%)823 (48.4%)412 (48.2%)
50–651187 (35.7%)333 (38.9%)666 (39.2%)333 (38.9%)

Marital status0.4300.930
Married2728 (82.0%)712 (83.3%)1411 (83.0%)712 (83.3%)
Single/widow597 (18.0%)143 (16.7%)288 (17.0%)143 (16.7%)

Ethnicity0.7740.740
Han3311 (99.6%)851 (99.5%)1693 (99.6%)851 (99.5%)
Others14 (0.42%)4 (0.47%)6 (0.35%)4 (0.47%)

Occupation0.7120.144
Farmer3209 (96.5%)828 (96.8%)1663 (97.9%)828 (96.8%)
Others116 (3.49%)27 (3.16%)36 (2.12%)27 (3.16%)

Educational status0.1120.539
≤6 years1021 (30.7%)238 (27.8%)452 (26.6%)238 (27.8%)
>6 years2304 (69.3%)617 (72.2%)1247 (73.4%)617 (72.2%)

Route of infection<0.0010.577
Others719 (21.6%)120 (14.0%)1445 (85.1%)735 (86.0%)
Plasma2606 (78.4%)735 (86.0%)254 (14.9%)120 (14.0%)

Time on HIV positive (years)0.0660.735
<3683 (20.5%)159 (18.6%)82 (4.83%)36 (4.21%)
3–81013 (30.5%)295 (34.5%)888 (52.3%)456 (53.3%)
>81629 (49.0%)401 (46.9%)729 (42.9%)363 (42.5%)

Time on ART before second-line (years)<0.0010.974
<3323 (9.71%)36 (4.21%)322 (19.0%)159 (18.6%)
3–61756 (52.8%)456 (53.3%)586 (34.5%)295 (34.5%)
>61246 (37.5%)363 (42.5%)791 (46.6%)401 (46.9%)

Symptoms0.0690.924
No2083 (62.6%)565 (66.1%)1118 (65.8%)565 (66.1%)
Yes1242 (37.4%)290 (33.9%)581 (34.2%)290 (33.9%)

CD4 cell count (cells/μl)0.0020.902
>500719 (21.6%)149 (17.4%)315 (18.5%)149 (17.4%)
350–500686 (20.6%)162 (18.9%)311 (18.3%)162 (18.9%)
200–350973 (29.3%)301 (35.2%)588 (34.6%)301 (35.2%)
<200947 (28.5%)243 (28.4%)485 (28.5%)243 (28.4%)

Viral load0.8330.678
<5002069 (62.2%)536 (62.7%)1075 (63.3%)536 (62.7%)
500–10000636 (19.1%)156 (18.2%)323 (19.0%)156 (18.2%)
>10000620 (18.6%)163 (19.1%)301 (17.7%)163 (19.1%)

PSM, propensity score matching; HIV, human immunodeficiency virus; ART, antiretroviral therapy.