Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Table 3
Comparison of changes in mean anthropometric and laboratory indices within and between intervention groups.
Parameters
Subgroups
Ginger (mean ± SD), n = 27
Placebo (mean ± SD), n = 26
value independent t-test
Weight (kg)
Before
85.15 ± 17.95
81.69 ± 15.97
0.463
After
82.72 ± 18.07
82.81 ± 15.90
0.986
Change
−2.43 ± 1.23
1.12 ± 1.18
0.001
value paired t-test
0.001
0.001
BMI (kg/m2)
Before
31.17 ± 5.28
31.29 ± 5.12
0.928
After
30.27 ± 5.32
31.71 ± 4.99
0.315
Change
−0.90 ± 0.46
0.42 ± 0.43
0.001
value paired t-test
0.001
0.001
Waist size (cm)
Before
110.30 ± 11.52
109.5 ± 13.92
0.821
After
106.33 ± 11.25
109.19 ± 11.41
0.363
Change
−3.96 ± 1.81
−0.31 ± 8.97
0.043
value paired t-test
0.001
0.863
TSH
Before
3.62 ± 2.21
2.87 ± 1.88
0.185
After
2.76 ± 1.72
3.81 ± 1.95
0.042
Change
−0.89 ± 1.33
0.95 ± 1.45
0.001
value paired t-test
0.001
0.003
FBS
Before
99.74 ± 13.56
86.19 ± 8.32
0.001
After
88.52 ± 10.41
93.15 ± 8.78
0.086
Change
−11.65 ± 6.55
6.96 ± 7.51
0.001
value paired t-test
0.001
0.001
TG
Before
229.52 ± 106.5
163.04 ± 79.49
0.013
After
175.03 ± 80.28
203.93 ± 104.52
0.266
Change
−56.59 ± 67.57
40.89 ± 57.44
0.001
value paired t-test
0.001
0.001
TChol
Before
181.56 ± 41.54
170.88 ± 37.11
0.329
After
162.89 ± 32.87
181.27 ± 37.21
0.062
Change
−19.38 ± 24.02
10.38 ± 16.66
0.001
value paired t-test
0.001
0.004
IPAQ
Before
200.36 ± 95.69
200.35 ± 61.44
1.000
After
200.36 ± 95.28
200.28 ± 60.46
0.997
value paired t-test
0.995
0.915
BMI: body mass index; TSH: thyroid-stimulating hormone; FBS: fasting blood sugar; TG: triglyceride; TChol: total cholesterol; IPAQ: International Physical Activity Questionnaire.