Research Article
Phytochemical Analysis and In Vitro and In Vivo Pharmacological Evaluation of Parthenium hysterophorus Linn
Table 5
The analgesic effect of crude extracts and various fractions of P. hysterophorus.
| Treatment | Dose (mg/kg) | No. of writhing |
| Normal saline | 10 ml/kg | 65.77 ± 3.46 | Diclofenac sodium | 10 | 17.67 ± 1.14 |
| MeOH | 25 | 51.48 ± 2.45 | 50 | 32.76 ± 1.19 | 100 | 16.87 ± 1.00 |
| Hexane | 25 | 66.85 ± 2.41 | 50 | 48.45 ± 1.17 | 100 | 32.54 ± 1.99 |
| Aqueous | 25 | 60.87 ± 2.67 | 50 | 41.45 ± 1.56 | 100 | 25.45 ± 1.98 |
| Ethyl acetate | 25 | 55.54 ± 2.49 | 50 | 33.76 ± 1.90 | 100 | 18.98 ± 1.71 |
| Chloroform | 25 | 61.45 ± 2.40 | 50 | 42.98 ± 1.14 | 100 | 26.98 ± 1.98 |
| Butanol | 25 | 48.45 ± 2.41 | 50 | 29.98 ± 1.98 | 100 | 14.96 ± 1.78 |
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