Research Article

Phytochemical Analysis and In Vitro and In Vivo Pharmacological Evaluation of Parthenium hysterophorus Linn

Table 5

The analgesic effect of crude extracts and various fractions of P. hysterophorus.

TreatmentDose (mg/kg)No. of writhing

Normal saline10 ml/kg65.77 ± 3.46
Diclofenac sodium1017.67 ± 1.14

MeOH2551.48 ± 2.45
5032.76 ± 1.19
10016.87 ± 1.00

Hexane2566.85 ± 2.41
5048.45 ± 1.17
10032.54 ± 1.99

Aqueous2560.87 ± 2.67
5041.45 ± 1.56
10025.45 ± 1.98

Ethyl acetate2555.54 ± 2.49
5033.76 ± 1.90
10018.98 ± 1.71

Chloroform2561.45 ± 2.40
5042.98 ± 1.14
10026.98 ± 1.98

Butanol2548.45 ± 2.41
5029.98 ± 1.98
10014.96 ± 1.78