Research Article

Citrus Flavone Tangeretin Inhibits CRPC Cell Proliferation by Regulating Cx26, AKT, and AR Signaling

Figure 5

Molecular docking analysis of tangeretin, AR, and Cx26. (a) Molecular structure of tangeretin. (b) Molecular docking of tangeretin onto the crystal structure of AR complexes (PDB ID: 5VO4) with a docking score of –3.0. (c) Molecular docking of tangeretin onto the crystal structure of Cx26 complexes (PDB ID: 5ER7) with a docking score of –6.3. The dotted green line represents hydrogen bonding. AR, androgen receptor and Cx26, connexin 26.
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