Study on the Mechanism of Compound Kidney-Invigorating Granule for Osteoporosis based on Network Pharmacology and Experimental Verification

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Name</td><td class="align_center">Betweenness centrality</td><td class="align_center">Closeness centrality</td><td class="align_center">Degree</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">JUN</td><td class="align_center">0.14728269</td><td class="align_center">0.46551724</td><td class="align_center">27</td></tr><tr><td class="align_left">TP53</td><td class="align_center">0.1435125</td><td class="align_center">0.43724696</td><td class="align_center">25</td></tr><tr><td class="align_left">TNF</td><td class="align_center">0.11585625</td><td class="align_center">0.42687747</td><td class="align_center">25</td></tr><tr><td class="align_left">AKT1</td><td class="align_center">0.10719742</td><td class="align_center">0.41698842</td><td class="align_center">22</td></tr><tr><td class="align_left">MAPK1</td><td class="align_center">0.07457652</td><td class="align_center">0.421875</td><td class="align_center">19</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Top 5 hub genes of treating OP of CKG and topological values.</div>

Evidence-Based Complementary and Alternative Medicine

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Table 3

Table 3: Study on the Mechanism of Compound Kidney-Invigorating Granule for Osteoporosis based on Network Pharmacology and Experimental Verification 