Antidiarrheal Effect of 80% Methanol Extract and Fractions of the Leaves of Ocimum lamiifolium in Swiss Albino Mice

Table 5

In vivo antidiarrheal indices (ADI) of 80% methanol crude extract and fractions of the leaves of O. lamiifolium.

Treatment	D freq (from castor oil-induced diarrhea)	G meq (from charcoal meal test)	P Freq (from castor oil-induced diarrhea)	ADI
NC	—	—	—	—
PC	160.23	49.67	68.12	81.54
CE 100	36.54	9.59	22.89	20.02
CE 200	48.54	15.09	36.51	29.90
CE 400	88.89	21.91	63.76	49.89
BF 100	29.25	13.93	13.62	17.7
BF 200	39.47	16.62	22.89	24.67
BF 400	90.05	29.60	45.50	49.5
DF 100	21.35	5.37	9.26	10.20
DF 200	31.88	11.54	18.26	18.87
DF 400	82.16	25.12	40.87	43.86
NC	—	—	—	—
PC	165.49	50.07	71.43	83.96
HF 100	42.48	9.68	42.86	26.02
HF 200	55.45	19.80	57.14	39.73
HF 400	98.81	28.23	62.00	55.71

NC = negative control (dissolved in distilled water), PC = positive control (dissolved in distilled water), CE = crude extract, BF = n-butanol fraction, DF = distilled water fraction, NC = negative control (dissolved in 2% tween-80), PC = positive control (dissolved in 2% tween-80), HF = n-hexane fraction.