Pinocembrin Reduces Keratinocyte Activation and Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis in BALB/c Mice through the Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Pathway

Figure 7

Effects of pinocembrin on spleen weight and spleen weight to body weight ratio. (a) Spleen weight. (b) Spleen weight to body weight ratio. On day 6 after IMQ challenge, the mice were euthanized, and the spleen weights and body weights were recorded. Data are expressed as mean ± SEM (n = 5 for IMQ-treated animals and n = 3 for Naive). , , and compared with the vehicle group, determined using Student’s two-tailed t-test.

(a)

(b)