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| Cancer | Treatment | Primary outcome | Therapeutic effect |
|
| Hepatocellular carcinoma [64] | Jianpi Liqi Fang and transcatheter arterial chemoembolization | Karnofsky performance status and traditional Chinese medicine (TCM) syndrome scores | Serum aspartate aminotransferase levels and total bilirubin levels decreased; Fibulin-5 displayed the largest difference |
|
| Postoperative colorectal cancer [65] | Bushen-Jianpi-Jiedu decoction combined with chemotherapeutic drugs (oxaliplatin) | Progression-free survival (PFS) and Karnofsky performance score (KPS) | Prolongs the survival and improves Karnofsky performance status |
|
| Nonsmall cell lung cancer [66] | Kangliu Jiandu formula combined with chemotherapy | Improvement rate of traditional Chinese medicine syndrome, curative effect of TCM syndrome, Karnofsky performance status (KPS) score, European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire-Lung Cancer | Significantly decreased the symptom area of QLQ-C30 and QLQ-LC13 score and increased the overall health status score of QLQ-C30, which were better than the control group |
|
| Breast cancer [67] | Chinese herbal medicine combined with Western medicine | Quality of life, frequency of symptom distress, and clinical safety | Higher red blood cell counts and lower liver function |
|
| Castration-resistant prostate cancer [68] | Fuyang Huayu prescription combined with chemotherapy (intravenous injection of docetaxel plus oral prednisone) | Level of serum prostate-specific antigen (PSA), Karnofsky physical condition scores, function assessment of cancer therapy-prostate (FACT-P) scores, and TCM symptom scores | Karnofsky, FACT-P, and TCM symptom scores were all markedly improved |
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