San-Huang-Chai-Zhu Formula Ameliorates Liver Injury in Intrahepatic Cholestasis through Suppressing SIRT1/PGC-1α-Regulated Mitochondrial Oxidative Stress

Figure 3

Hepatic mitochondrial function and oxidative stress were assessed by the ELISA test. (a) Malondialdehyde (MDA) level; (b) superoxide dismutase (SOD) level; (c) glutathione (GSH) level; (d) adenosine triphosphate (ATP) level; (e) 8-hydroxy-2′-deoxyguanosine (8-OHdG) level. (f) The relative mRNA expression of mtDNA in hepatic tissues was measured by qRT-PCR. and vs. the normal group. and vs. the model group. and vs. the high-dose SHCZF group. SHCZF promoted apoptosis in the hepatic tissues of IC rats.

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