Research Article

Regulatory Effects of Astragaloside IV on Hyperglycemia-Induced Mitophagy in Schwann Cells

Figure 1

Determination of the dose and duration of hyperglycemic exposure for constructing the hyperglycemia-induced autophagy model. (a) Two-day-old culture of Schwann cells. (b) Determination of the expression levels of LC3II and LC3I proteins 24, 48, and 72 h postexposure via Western blot assays. (c) Expression level of LC3 at different concentrations and duration of exposure to glucose. Statistical significance: , .
(a)
(b)
(c)