Network Pharmacology-Based Prediction and Verification of the Potential Mechanisms of He’s Yangchao Formula against Diminished Ovarian Reserve

Table 2

Docking results of the four hub targets with their corresponding compounds.

Mol ID	Compound	Target	Affinity (kcal/mol)
MOL000492	(+)-Catechin	AKT1	−7.4
MOL000546	Diosgenin	AKT1	−2.7
MOL000422	Kaempferol	AKT1	−7.1
MOL000098	Quercetin	AKT1	−7.2
MOL002959	3′-methoxydaidzein	AKT1	−8.4
MOL000492	(+)-Catechin	ESR1	−7.3
MOL002959	3′-methoxydaidzein	ESR1	−6
MOL003896	7-Methoxy-2-Methyl Isoflavone	ESR1	−6.6
MOL001927	Albiflorin	ESR1	−6.7
MOL000546	Diosgenin	ESR1	−8.1
MOL001002	Ellagic acid	ESR1	−9.6
MOL010586	Formononetin	ESR1	−6
MOL000354	Isorhamnetin	ESR1	−6.3
MOL000422	Kaempferol	ESR1	−7.2
MOL001924	Paeoniflorin	ESR1	−7
MOL000098	Quercetin	ESR1	−7.3
MOL000449	Stigmasterol	ESR1	−6.2
MOL001919	(3S,5R,8R,9R,10S,14S)-3,17-Dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9-hexahydro-1H-cyclopenta[a]phenanthrene-15,16-dione	ESR1	−8.6
MOL001941	Ammidin	ESR1	−8.6
MOL005320	Arachidonic acid	ESR1	−7.3
MOL008583	Beta-Sitosterol	ESR1	−8.1
MOL005043	Campest-5-En-3beta-Ol	ESR1	−6.6
MOL000953	CLR	ESR1	−6.4
MOL005440	Isofucosterol	ESR1	−6.9
MOL000211	Mairin	ESR1	−7.4
MOL008871	Marckine	ESR1	−7.9
MOL000184	Nsc63551	ESR1	−6.7
MOL001558	Sesamin	ESR1	−6.2
MOL000359	Sitosterol	ESR1	−6.7
MOL005384	Suchilactone	ESR1	−6.6
MOL007563	Yangambin	ESR1	−5.6
MOL000546	Diosgenin	P53	−6.6
MOL000098	Quercetin	P53	−7.7
MOL005944	Matrine	IL6	−5.9
MOL001924	Paeoniflorin	IL6	−6.7
MOL000098	Quercetin	IL6	−6.4