Bioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis

<div>KJK inhibits the activation of PI3K/AKT in UC mice induced by 2.5% DSS. (a) Representative immunoblotting images of p-PI3K, PI3K, p-AKT, AKT, and GAPDH. (b) and (c) Effect of KJK on the mRNA expression of <i>pi3k</i> and <i>akt</i> in the colon of mice with UC. (d, e) Effect of KJK on p-PI3K/PI3K and p-AKT/ AKT protein expression in the colon of mice with UC. Data are expressed as mean ± SEM. <i>n</i> = 3. 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Evidence-Based Complementary and Alternative Medicine

fig7

Figure 7

Figure 7: Bioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis 

Figure 7 | Bioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis 