Evaluation of the Mechanism of Jiedu Huazhuo Quyu Formula in Treating Wilson’s Disease-Associated Liver Fibrosis by Network Pharmacology Analysis and Molecular Dynamics Simulation

<div>Identification of core target genes through module analysis adopted for gene set enrichment analysis of the 6 core target genes. (a) Module 2 consisted of 30 nodes and 378 edges as identified by the MCODE plugin in Cytoscape 3.7.2. (b) The top 6 core target genes identified by the CytoNCA plugin. (c) Top 20 enriched GO-CC terms. (d) Top 20 enriched GO-MF terms. (e) Top 20 enriched GO-BP terms. (f) Top 20 enriched KEGG pathways.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5: Evaluation of the Mechanism of Jiedu Huazhuo Quyu Formula in Treating Wilson’s Disease-Associated Liver Fibrosis by Network Pharmacology Analysis and Molecular Dynamics Simulation 

Figure 5 | Evaluation of the Mechanism of Jiedu Huazhuo Quyu Formula in Treating Wilson’s Disease-Associated Liver Fibrosis by Network Pharmacology Analysis and Molecular Dynamics Simulation 