Research Article

Krüppel-Like Factor 2 Is a Gastric Cancer Suppressor and Prognostic Biomarker

Figure 5

Knockdown of KLF2 promotes the growth, proliferation, migration, and invasion of GC cells. (a) Western blot used to analyze E-cadherin, N-cadherin, Snail, vimentin, and Twist protein expression levels in HGC-27 cells knocked down for KLF2, after KLF2 knockdown in HGC-27 and AGS GC cell lines. (b-c) Cell viability measured by CCK-8 assay. (d-e) A colony formation assay used to analyze GC cell proliferation ability. (f-g) Wound healing assay used to assess the migration ability of GC cells. (h–j) Transwell assay used to analyze migration and invasion of GC .
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