Research Article

TP73-AS1 rs3737589 Polymorphism is Associated With the Clinical Stage of Colorectal Cancer

Table 4

The association between TP73-AS1 gene rs3737589 polymorphism and clinical stage of CRC.

Genotype or alleleIII + IV (n = 276)I + II (n = 300)ComparisonaOR (95% CI)a value

Genotype
 TT161 (58.3%)157 (52.3%)TC vs. TT0.98 (0.69–1.38)0.96
 TC106 (38.4%)107 (35.7%)CC vs. TT0.25 (0.12–0.54)0.0003
 CC9 (3.3%)36 (12.0%)C vs. T0.69 (0.53–0.89)0.006
Allele
 T428 (77.5%)421 (70.2%)(TC + CC) vs. TT0.79 (0.57–1.10)0.19
 C124 (22.5%)179 (29.8%)CC vs. (TC + TT)0.26 (0.12–0.56)0.0004

aAdjusted by age and gender.