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Natural Products and/or Isolated Compounds on Microbial Biofilms

Call for Papers

Infectious diseases represent a substantial proportion of deaths worldwide. Biofilms are the most common state of microbial growth found in nature and in patients infected with pathogenic organisms. Biofilms are communities of microorganisms that are attached to a substratum and encased in a self-produced extracellular matrix. Biofilms exhibit an altered phenotype; genetically identical cells express different genes and produce subpopulations of cell types. Microbial biofilms are ubiquitous, located in the human host, including the oral cavity, respiratory tract, gastrointestinal tract, and urinary tract. Biofilm has mostly a beneficial effect since its constant presence provides a resistance against possible pathogenic microorganisms. From a healthy state to a disease state, there is a change in populations of predominant bacteria and fungi. Cystic fibrosis, native valve endocarditis, otitis media, periodontitis, chronic prostatitis, and device-associated infections all appear to be caused by biofilm-associated microorganisms. Biofilm-related diseases often correlate with antibiotic resistance. Therefore, the discovery of innovative strategies to treat microbial biofilm is of great interest. Nature is an unexplored reservoir of novel phytopharmaceuticals. The potential of natural extracts to cure human infections has been well established to date even though, in many countries, the use of natural products continues to be practiced without regulations. The study of the effectiveness of natural products in vitro and in vivo including their toxicity could enhance existing treatment options to treat microbial harmful biofilm or to promote beneficial biofilm formation.

This special issue aims to highlight the recent research on natural products including animal products and/or isolated compounds alone or in association with conventional drugs for harmful biofilm prevention.

Both in vitro and in vivo studies are encouraged. We invite authors who are leading experts in the field to contribute with original articles that are not yet published or that are not currently under review by other journals to promote, integrate, and disseminate. The publication of articles in this special issue should provide a forum for researchers to share their recent findings and offer exposure of the published articles to the scientific community. We hope that the special issues will advance knowledge and stimulate new collaborations and new research directions.

Potential topics include but are not limited to the following:

  • Natural products including animal products and/or isolated compounds against harmful microbial biofilm
  • Natural products including animal products and/or isolated compounds for protection of beneficial biofilms
  • Studies on the use of natural products including animal products and/or isolated compounds in association with conventional drugs including delivery strategies
  • Novel nanoparticles for the delivery of natural products including animal products and/or isolated compounds active against bacterial or fungal biofilm
  • Elucidation of mechanism(s) of action of natural products and/or isolated compounds active against microbial biofilm

Authors can submit their manuscripts through the Manuscript Tracking System at https://mts.hindawi.com/submit/journals/ecam/nsmb/.

Submission DeadlineFriday, 6 July 2018
Publication DateNovember 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

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