Evidence-Based Complementary and Alternative Medicine

Natural Oxidative Medicines with Bioactive Functions for Chronic Disease Treatment


Publishing date
01 Dec 2022
Status
Published
Submission deadline
05 Aug 2022

Lead Editor
Guest Editors

1Harbin Institute of Technology, Harbin, China

2Central South University, Changsha, China

3Korea University of Technology, Cheonan, Republic of Korea


Natural Oxidative Medicines with Bioactive Functions for Chronic Disease Treatment

Description

Natural bioactive ingredients of oxidative medicines have been a focus of many studies owing to their low toxicity and side effects as well as their excellent efficacy. Bioactive ingredients are the main components extracted from herbs that have therapeutic properties. The bioactive ingredients have multilevel effects on the treatment of numerous chronic diseases, such as asthma, anti-inflammation, anti-infection, antimicrobial activity, and diabetes mellitus. Usually, the bioactive ingredients of conventional oxidative medicines have been divided into six categories concluding flavonoids, saponins, terpenoids, alkaloids, polysaccharides, and other organic acids. In addition, studies found that curcumin, magnolol, animal protein, photosensitizer, and reactive oxide species with antimicrobial activity have positive effects on chronic disease treatment. Active polyphenol curcumin as a pro-drug via oxidative activation into reactive metabolites showed excellent anti-inflammatory activities and antibacterial activities.

Although considerable efforts have been made in the application of these bioactive ingredients for chronic disease treatment, the lack of systematic studies on therapeutic mechanisms of these bioactive ingredients for disease treatment impedes the extensive application of these oxidative medicines in vivo. For example, the bioactivation of curcumin will occur in vitro, while bioactivation is insufficient in vivo. Therefore, the evaluation and design of clinical trials of curcumin and other medicinal polyphenols should be considered. As well as this, the functional mechanism of bioactive ingredients must be highlighted in future research. The safety evaluation and bioavailability of bioactive ingredients are important indexes for the development of oxidative medicines. Meanwhile, the physicochemical and biological properties of curcumin and other bioactive ingredients should be further discussed before their clinical usage. Furthermore, the industrial production of natural bioactive ingredients is still a huge challenge.

This Special Issue aims to summarize the frontier knowledge of underlying mechanisms and physicochemical properties of bioactive ingredients in chronic disease treatment and provide fully integrated, reliable information for clinic applications of bioactive ingredients as oxidative medicines. We welcome original research and review articles.

Potential topics include but are not limited to the following:

  • Therapeutic properties of natural bioactive ingredients
  • Multilevel effects of bioactive ingredients on the treatment of chronic diseases
  • Application of bioactive ingredients
  • Safety evaluation of bioactive ingredients
  • Bioavailability of natural bioactive ingredients
  • Functional mechanisms of bioactive ingredients for chronic disease treatment
  • Synthesized methods and instrumental analysis of natural bioactive ingredients
  • Industrial production of medicines
  • Clinical studies for disease treatment
  • Mathematical models for the oxidative medicines

Articles

  • Special Issue
  • - Volume 2023
  • - Article ID 9808315
  • - Retraction

Retracted: Effects of Shenkang Injection Combined with Jinshuibao on Early Diabetic Nephropathy and Effects on Coagulation Fibrinolysis System and Urinary Protein

Evidence-Based Complementary and Alternative Medicine
  • Special Issue
  • - Volume 2023
  • - Article ID 9816492
  • - Retraction

Retracted: A Critical Scrutiny on Liposomal Nanoparticles Drug Carriers as Modelled by Topotecan Encapsulation and Release in Treating Cancer

Evidence-Based Complementary and Alternative Medicine
  • Special Issue
  • - Volume 2023
  • - Article ID 9803084
  • - Retraction

Retracted: Potential Molecular Mechanism of Guishen Huoxue Decoction against Intrauterine Adhesion Based on Network Pharmacology

Evidence-Based Complementary and Alternative Medicine
  • Special Issue
  • - Volume 2023
  • - Article ID 9872906
  • - Retraction

Retracted: Influence of Adenoid Hypertrophy on Malocclusion and Maxillofacial Development in Children

Evidence-Based Complementary and Alternative Medicine
  • Special Issue
  • - Volume 2023
  • - Article ID 9804184
  • - Retraction

Retracted: Analysis of the Demand for Continuing Education of Nurses in the Department of Infectious Diseases and Its Influencing Factors

Evidence-Based Complementary and Alternative Medicine
  • Special Issue
  • - Volume 2023
  • - Article ID 9769745
  • - Retraction

Retracted: Analysis on Value of Continuous Nursing Based on WeChat in Improving Healthy Quality of Life and Self-Management Behavior of Patients with Diabetic Nephropathy

Evidence-Based Complementary and Alternative Medicine
  • Special Issue
  • - Volume 2023
  • - Article ID 9784620
  • - Retraction

Retracted: Investigation on Depression of College Students Majoring in Physical Education and Nonphysical Education: A StudyBased on the Age Region and Gender of 374 Students

Evidence-Based Complementary and Alternative Medicine
  • Special Issue
  • - Volume 2023
  • - Article ID 9808742
  • - Retraction

Retracted: Analysis of the Effectiveness of the Nurse-Led “Outpatient-Ward-Home” Management Model in Chronic Kidney Patients

Evidence-Based Complementary and Alternative Medicine
  • Special Issue
  • - Volume 2023
  • - Article ID 9878042
  • - Retraction

Retracted: Study on the Changes and Significance of Immune State and Cycokines in Children with Adenovirus Pneumonia

Evidence-Based Complementary and Alternative Medicine
  • Special Issue
  • - Volume 2023
  • - Article ID 9823862
  • - Retraction

Retracted: A Retrospective Study of Diaphragmatic Breathing Training Combined with Discharge Care Bundles in Patients with Chronic Obstructive Pulmonary Disease

Evidence-Based Complementary and Alternative Medicine

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