Evidence-Based Complementary and Alternative Medicine

Therapeutic Approaches to Neuroprotective Activity by Complementary and Alternative Medicines


Publishing date
10 Aug 2012
Status
Published
Submission deadline
10 Feb 2012

1Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkey; Pharmacognosy and Pharmaceutical Botany Unit, Faculty of Pharmacy, Eastern Mediterranean University, Gazimagosa, North Cyprus, Turkey

2Department Pharmaceutical Sciences, Faculty of Pharmacy, Nutrition and Health Sciences, University of Calabria, 87036 Arcavacata di Rende (CS), Italy

3Center for Pharmaceutical Biotechnology, College of Pharmacy, University of Illinois at Chicago, Molecular Biology Research Building, 900 South Ashland Avenue, Chicago, IL 60607-7173, USA


Therapeutic Approaches to Neuroprotective Activity by Complementary and Alternative Medicines

Description

Neurodegeneration is the processes resulting from the death and functional or structural loss of cells in the central nervous system, and neuroprotection can be described as an endeavor to sustain the maximum probable integrity of interactions in the brain. Prevalence of neurodegenerative diseases (NDs) including Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis (ALS), epilepsy, head trauma, and stroke is on increase, and appraisements by WHO advocate that the age-associated neurodegenerative disorders will be the world's third leading cause of death, after cardiovascular diseases and overtaking cancer by the year 2040. Since the NDs have a slow progressive nature with a complex pathophysiology, treatment strategies are available only at symptomatic level and, in fact, it is not possible, yet, to seize or revert these diseases.

The etiology is multifactorial, which is variable from genetic to environmental factors, and the mechanisms underlying these diseases are poorly elucidated. As the current treatments are inadequate and also require an enormous cost, NDs still represent a major challenge to modern drug research.

Relevantly, an intensive research is being conducted on neuroprotective effects of many plant species. Clinical applications, efficacy in humans and safety, also interactions of potential neuroprotective plant products are, therefore, of tremendous importance. On this occasion, plant scientists performing research linked to neurodegeneration are invited to contribute their results to this special issue. Potential topics include, but are not limited to:

  • In vitro and in vivo evaluation of neuroprotective activity of traditionally used plants with their quality and compositional analysis
  • Preclinical studies on neuroprotective effects of plants and their metabolites
  • Clinical studies on neuroprotective effects of plants and their metabolites
  • Structure-activity relationship of the molecules with neuroprotective potentials
  • Neuron cell culture studies with plants and their metabolites
  • Mechanism-based studies in neuroprotection by plant products
  • Interactions, efficacies, and adverse effects of plant products with neuroprotective activity

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ecam/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 376068
  • - Editorial

Therapeutic Approaches to Neuroprotective Activity by Complementary and Alternative Medicines

Ilkay Erdogan Orhan | Monica Rosa Loizzo | Mahmud Tareq Hassan Khan
  • Special Issue
  • - Volume 2012
  • - Article ID 191632
  • - Review Article

Chinese Medicine in Diabetic Peripheral Neuropathy: Experimental Research on Nerve Repair and Regeneration

Yuanlin Piao | Xiaochun Liang
  • Special Issue
  • - Volume 2012
  • - Article ID 156521
  • - Research Article

Mitigation of H2O2-Induced Mitochondrial-Mediated Apoptosis in NG108-15 Cells by Novel Mesuagenin C from Mesua kunstleri (King) Kosterm

Gomathi Chan | Muhamad Noor Alfarizal Kamarudin | ... | Habsah Abdul Kadir
  • Special Issue
  • - Volume 2012
  • - Article ID 478190
  • - Research Article

Herbal Extracts Combination (WNK) Prevents Decline in Spatial Learning and Memory in APP/PS1 Mice through Improvement of Hippocampal Aβ Plaque Formation, Histopathology, and Ultrastructure

Wei-hong Cong | Bin Yang | ... | Jian-xun Liu
  • Special Issue
  • - Volume 2012
  • - Article ID 682720
  • - Research Article

A Pilot Study for the Neuroprotective Effect of Gongjin-dan on Transient Middle Cerebral Artery Occlusion-Induced Ischemic Rat Brain

Yun-Young Sunwoo | Sang In Park | ... | Young-Min Han
  • Special Issue
  • - Volume 2012
  • - Article ID 701289
  • - Research Article

Anxiolytic-Like Effects of Compound Zhi Zhu Xiang in Rats

Yan-Li Wang | Jin-Li Shi | ... | Jian-You Guo
  • Special Issue
  • - Volume 2012
  • - Article ID 591298
  • - Research Article

Early Blockade of TLRs MyD88-Dependent Pathway May Reduce Secondary Spinal Cord Injury in the Rats

An-hui Yao | Li-yun Jia | ... | Fang Kuang
  • Special Issue
  • - Volume 2012
  • - Article ID 459894
  • - Research Article

Neuroprotective Activity of Sibjeondaebo-tang on A Peptide-Induced Damages

Hyeon Ju Yim | Jung Hwa Lim | ... | In Chul Jung
  • Special Issue
  • - Volume 2012
  • - Article ID 946259
  • - Review Article

Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential

Ilkay Erdogan Orhan
  • Special Issue
  • - Volume 2012
  • - Article ID 636091
  • - Research Article

Rhynchophylline Protects Cultured Rat Neurons against Methamphetamine Cytotoxicity

Dan Dan Xu | Robin Hoeven | ... | William Chi-Shing Cho
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate28%
Submission to final decision72 days
Acceptance to publication43 days
CiteScore2.010
Impact Factor1.984
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