Evidence-Based Complementary and Alternative Medicine

Role of Natural Products in Ameliorating Drugs and Chemicals Toxicity


Publishing date
19 Aug 2016
Status
Published
Submission deadline
01 Apr 2016

1Suez Canal University, Ismailia, Egypt

2Cairo University, Giza, Egypt

3University of Pisa, Pisa, Italy

4“Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania


Role of Natural Products in Ameliorating Drugs and Chemicals Toxicity

Description

Drugs’ and chemicals’ toxicity is a common crisis in human and animals. Overdosing and drug abuse are the main issues of toxicity. Pesticides, water pollution with heavy metals, and veterinary drug residues constitute the high incidence of reported cases of toxicities. Besides, toxins from different origin as mycotoxines and microbial toxins including food poisoning organisms can affect human and animals.

There is an increasing worldwide demand for ethnobotanical preparations as they have wide acceptance by consumers and are safe for the environment. Moreover, they are used to protect the body and improve the immune system, without the untoward effects commonly associated with synthetic chemical agents. Many medicinal herbs and their active ingredients, such as flavonoids and polyphenolic compounds (proanthocyanidins, cinnamic acids, curcumin, berberine, etc.), have been studied extensively by using various toxicological animal models. Targeting of the mechanisms by these agents remains the primary focus for several diseases and toxicities.

This special issue is dedicated to integrate past and present use of plants reporting traditional/folk medicinal use. Researchers are invited to submit original research and review articles on a range of topics to explore the pharmacotoxicological mechanisms of phyto-products and their active constituents for prevention and treatment of drugs’ and chemicals’ toxicity.

Potential topics include, but are not limited to:

  • The therapeutic application of dietary supplements against drugs and chemicals toxicity
  • Natural products in the development of drugs to overcome toxicities
  • Separation and identification of active constituents of high antioxidant efficacy
  • Polyphenols from foods for prevention of drugs and chemicals toxicity
  • Elucidation of mechanism of phytochemicals that have antidotal activity
  • Herb-drug interaction and herb-chemical interaction and their mechanism

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 7879406
  • - Editorial

Role of Natural Products in Ameliorating Drugs and Chemicals Toxicity

Mohamed M. Abdel-Daim | Salah M. Aly | ... | Sorin Ursoniu
  • Special Issue
  • - Volume 2016
  • - Article ID 2046298
  • - Research Article

Membrane Stabilization and Detoxification of Acetaminophen-Mediated Oxidative Onslaughts in the Kidneys of Wistar Rats by Standardized Fraction of Zea mays L. (Poaceae), Stigma maydis

S. Sabiu | F. H. O’Neill | A. O. T. Ashafa
  • Special Issue
  • - Volume 2016
  • - Article ID 7387286
  • - Research Article

Unsweetened Natural Cocoa Powder Has the Potential to Attenuate High Dose Artemether-Lumefantrine-Induced Hepatotoxicity in Non-Malarious Guinea Pigs

Isaac Julius Asiedu-Gyekye | Kennedy Kwami Edem Kukuia | ... | Alexander Kwadwo Nyarko
  • Special Issue
  • - Volume 2016
  • - Article ID 7659684
  • - Research Article

Chitosan and Sodium Alginate Combinations Are Alternative, Efficient, and Safe Natural Adjuvant Systems for Hepatitis B Vaccine in Mouse Model

Nourhan H. AbdelAllah | Nourtan F. Abdeltawab | ... | Magdy A. Amin
  • Special Issue
  • - Volume 2016
  • - Article ID 4976791
  • - Research Article

Thin Layer Chromatography-Bioautography and Gas Chromatography-Mass Spectrometry of Antimicrobial Leaf Extracts from Philippine Piper betle L. against Multidrug-Resistant Bacteria

Demetrio L. Valle | Juliana Janet M. Puzon | ... | Windell L. Rivera
  • Special Issue
  • - Volume 2016
  • - Article ID 8692343
  • - Research Article

Effect of Kangfuxin Solution on Chemo/Radiotherapy-Induced Mucositis in Nasopharyngeal Carcinoma Patients: A Multicenter, Prospective Randomized Phase III Clinical Study

Yangkun Luo | Mei Feng | ... | Jinyi Lang
  • Special Issue
  • - Volume 2016
  • - Article ID 4579149
  • - Research Article

Evaluation of Hepatoprotective Activity of Adansonia digitata Extract on Acetaminophen-Induced Hepatotoxicity in Rats

Abeer Hanafy | Hibah M. Aldawsari | ... | Seham El-Sayed Abdel-Hady
  • Special Issue
  • - Volume 2016
  • - Article ID 9470954
  • - Research Article

Satkara (Citrus macroptera) Fruit Protects against Acetaminophen-Induced Hepatorenal Toxicity in Rats

Sudip Paul | Md. Aminul Islam | ... | Md. Ibrahim Khalil
  • Special Issue
  • - Volume 2016
  • - Article ID 8098561
  • - Research Article

Electroacupuncture Reduces Weight Gain Induced by Rosiglitazone through PPARγ and Leptin Receptor in CNS

Xinyue Jing | Chen Ou | ... | Bing-Mei Zhu
  • Special Issue
  • - Volume 2016
  • - Article ID 8912184
  • - Research Article

The Protective Effects of Isoliquiritigenin and Glycyrrhetinic Acid against Triptolide-Induced Oxidative Stress in HepG2 Cells Involve Nrf2 Activation

Ling-Juan Cao | Huan-De Li | ... | Bi-Kui Zhang
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate27%
Submission to final decision68 days
Acceptance to publication33 days
CiteScore2.900
Impact Factor1.813
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