Evidence-Based Complementary and Alternative Medicine

Toxic versus Therapeutic Effects of Natural Products on Reproductive Disorders


Publishing date
01 Aug 2019
Status
Published
Submission deadline
05 Apr 2019

1Universidade Estadual Paulista, Botucatu, Brazil

2Federal University of Grande Dourados, Dourados, Brazil

3State University of Londrina, Londrina, Brazil

4Harvard T.H. Chan School of Public Health, Boston, USA


Toxic versus Therapeutic Effects of Natural Products on Reproductive Disorders

Description

Reproductive healthcare addresses reproductive processes, functions, and systems at all stages of life. It involves the sexual health of both men and women, as well as maternal and child health. In this sense, the interest in alternative therapies has markedly increased and the use of products of natural origin has become an important tool for the prevention and/or treatment of reproductive disorders. However, their use can have beneficial or adverse effects, and researches are required to exploit these effects. Medicinal plants can negatively affect the reproductive systems of men and women, and if the exposure occurs before and after the conception they can affect the parents as well as the offspring. Despite their possible toxic effects, preclinical studies of reproductive toxicity in the majority of the products derived from plants are still scarce, and research in this area should be encouraged. Moreover, many plant species may be investigated for their therapeutic properties. Some natural products may be used as an alternative medicine for reproductive health as long as their mechanisms and toxicity studies are carefully analyzed. Several species have been used to treat reproductive disorders, such as sexual dysfunction, infertility, and gynecological disorders, among others. Natural compounds with antioxidant properties have also proven to be beneficial in experimental models of reproductive toxicity and may preserve the fertility of patients receiving chemotherapy. Furthermore, many plants are known for their antifertility effects which make them an important source of new contraceptives in males. Thus, new drugs and therapies may be developed through comprehensive investigation of the bioactivity of several natural compounds.

This special issue intends to compile original research and review articles which address the influence of natural products on reproduction. Studies focusing on detecting potential reproductive health hazards of natural products as well as therapeutic effects of these compounds to treat reproductive disorders are welcome.

Potential topics include but are not limited to the following:

  • Natural compounds to prevent or minimize the reproductive toxicity induced by drugs
  • Natural products and contraception
  • Efficacy and selectivity of medicinal plants to the treatment of reproductive disorders
  • Toxicity reproductive evaluation after treatment with natural products
  • Effects of the exposure to natural compounds during the gestational or lactation period
  • Medicinal plants as endocrine disruption
  • Toxic versus therapeutic effects of medicinal plants on mother and infant

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 9791506
  • - Editorial

Toxic versus Therapeutic Effects of Natural Products on Reproductive Disorders

Arielle Cristina Arena | Cândida Aparecida Leite Kassuya | ... | Wellerson Rodrigo Scarano
  • Special Issue
  • - Volume 2019
  • - Article ID 8494567
  • - Research Article

Shengjing Capsule Improves Spermatogenesis through Upregulating Integrin α6/β1 in the NOA Rats

Jiamin Wang | Shankun Zhao | ... | Zhigang Zhao
  • Special Issue
  • - Volume 2019
  • - Article ID 6369132
  • - Research Article

Aconiti Lateralis Radix Preparata, the Dried Root of Aconitum carmichaelii Debx., Improves Benign Prostatic Hyperplasia via Suppressing 5-Alpha Reductase and Inducing Prostate Cell Apoptosis

Jinbong Park | Dong-Hyun Youn | Jae-Young Um
  • Special Issue
  • - Volume 2019
  • - Article ID 8619283
  • - Research Article

Nymphaea lotus Linn. (Nymphaeaceae) Alleviates Sexual Disability in L-NAME Hypertensive Male Rats

Poumeni Mireille Kameni | Djomeni Paul Desire Dzeufiet | ... | Pierre Kamtchouing
  • Special Issue
  • - Volume 2019
  • - Article ID 7249679
  • - Review Article

Research Progress of Male Reproductive Toxicity of Chinese Materia Medicas

Sicong Li | Chao Li | ... | Mei Han
  • Special Issue
  • - Volume 2019
  • - Article ID 5346518
  • - Research Article

Reproductive Regulation and Oxidative Stress Alleviation of Chinese Herbal Medicine Therapy in Ovariectomised Mouse Model

Chung-Hsin Wu | Sheue-Er Wang | ... | Ming-Chung Lee
  • Special Issue
  • - Volume 2019
  • - Article ID 2089586
  • - Research Article

Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms

Yong Wang | Jing-zhen Wu | ... | Xu Qi
  • Special Issue
  • - Volume 2019
  • - Article ID 7543460
  • - Research Article

Brain Cortical and Hippocampal Dopamine: A New Mechanistic Approach for Eurycoma longifolia Well-Known Aphrodisiac Activity and Its Chemical Characterization

Shahira M. Ezzat | Marwa I. Ezzat | ... | Shanaz O. Mohamed
  • Special Issue
  • - Volume 2019
  • - Article ID 4341592
  • - Research Article

Rho-Kinase II Inhibitory Potential of Eurycoma longifolia New Isolate for the Management of Erectile Dysfunction

Shahira M. Ezzat | Mona M. Okba | ... | Shanaz O. Mohamed
  • Special Issue
  • - Volume 2019
  • - Article ID 8453635
  • - Research Article

Morinda Officinalis Polysaccharides Attenuate Varicocele-Induced Spermatogenic Impairment through the Modulation of Angiogenesis and Relative Factors

Zhu Zhu | Xiaozhen Zhao | ... | Wei Wang
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate27%
Submission to final decision68 days
Acceptance to publication33 days
CiteScore2.900
Impact Factor1.813
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