Evidence-Based Complementary and Alternative Medicine

The Therapeutic Value of Medicinal and Edible Plants in Digestive System Diseases


Publishing date
01 Jul 2022
Status
Closed
Submission deadline
04 Mar 2022

1Universidade do Vale do Itajaí, Itajaí, Brazil

2Chinese Academy of Sciences, Beijing, China

3EBSERH - Hospital Universitário Júlio Muller, Cuiabá, Brazil

4Universidade Comunitária da Região de Chapecó, Chapecó, Brazil

This issue is now closed for submissions.
More articles will be published in the near future.

The Therapeutic Value of Medicinal and Edible Plants in Digestive System Diseases

This issue is now closed for submissions.
More articles will be published in the near future.

Description

The human digestive system consists of a long tube known as the gastrointestinal (GI) tract plus the accessory organs of digestion. The GI tract is divided into several parts, each with special characteristics: the mouth, esophagus, stomach, and small and large intestines. In addition, there are also accessory glands associated with this system, such as: liver, pancreas, and gallbladder. The main function of GI tract is the digestion of foods to become simpler molecules suitable for absorption to provide the nutrients necessary for normal functionality of the body. There are several disorders that affect the human digestive system and many of them have a high prevalence worldwide and have become increasingly common over the last few years. Digestive diseases range from the occasional upset stomach to the more life-threatening colon cancer and encompass disorders of the GI tract, liver, gallbladder, and pancreas.

The current approved treatments for many digestive diseases are inefficient or associated with side effects. For example, proton pump inhibitors (omeprazole, lansoprazole) may cause nausea, abdominal pain, constipation, and diarrhea, and H2 receptor antagonists (ranitidine) may suffer loss of effectiveness due to tolerance. For this reason, the attention of the scientific community has been directed towards the search for new therapies in the treatment of such diseases. There have been many experimental and clinical studies emerging during the last decade looking to investigate the potential application of herbal products, mainly medicinal and/or edible plants, to prevent or treat these disorders when used either as complementary or alternative treatments. The results of such studies have reinforced the importance of herbal preparations for the development of new drugs to treat such disorders and have shown their adjuvant role in enhancing the effectiveness of the approved treatment in progress.

However, despite popular use, different plant species still lack scientific contributions to validate their use. Therefore, this Special Issue aims to bring together articles that promote the discussion of the therapeutic value of medicinal and edible plants in digestive system diseases. We aim to highlight research that can contribute to the improvement and innovation of clinical practice within gastroenterology. Original research and review articles are welcome.

Potential topics include but are not limited to the following:

  • Studies at both the experimental, pre-clinical and clinical level concerning the potential role of plant extracts used in folk medicine or from edible plants to prevent or treat gastroesophageal reflux disease, gastritis, and gastric ulcers
  • The potential role of plant extracts used in folk medicine or from edible plants to treat Crohn's disease, alimentary mucositis, irritable bowel syndrome, and gallstones
  • The treatment of diseases of the liver, such as hepatitis and liver damage, using plant extracts or edible plants
  • Investigations concerning isolated compounds from natural sources to prevent or treat digestive system diseases
  • Safety of plant extracts or isolated active compounds in the digestive system

Articles

  • Special Issue
  • - Volume 2022
  • - Article ID 8773527
  • - Research Article

Integrating Network Pharmacology and In Vivo Model to Investigate the Mechanism of Biheimaer in the Treatment of Functional Dyspepsia

Chun Wang | Nuermanati Huanbieke | ... | Zhi-Jian Li
  • Special Issue
  • - Volume 2022
  • - Article ID 4328571
  • - Research Article

Toxicity and Antiulcer Properties of Ipomoea wightii (Wall.) Choisy Leaves: An In Vivo Approach Using Wistar Albino Rats

Saikumar Sathyanarayanan | Puthanpura Sasidharan Sreeja | ... | Thangaraj Parimelazhagan
  • Special Issue
  • - Volume 2022
  • - Article ID 4041402
  • - Research Article

Citrus unshiu Peel Attenuates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice due to Modulation of the PI3K/Akt Signaling Pathway and MAPK and NF-κB

Se Hui Lee | Jin A. Lee | ... | Seong-Soo Roh
  • Special Issue
  • - Volume 2022
  • - Article ID 6134128
  • - Research Article

Lupeol Stearate Accelerates Healing and Prevents Recurrence of Gastric Ulcer in Rodents

Lincon Bordignon Somensi | Philipe Costa | ... | Luisa Mota da Silva
  • Special Issue
  • - Volume 2022
  • - Article ID 4651432
  • - Research Article

Study on the Potential Molecular Mechanism of Xihuang Pill in the Treatment of Pancreatic Cancer Based on Network Pharmacology and Bioinformatics

Jing Wang | Yaxing Zhang | ... | Peitong Zhang
  • Special Issue
  • - Volume 2022
  • - Article ID 4797884
  • - Research Article

Antioxidant and Antivenom Potential of an Essential Oil, 4-(2-Oxo-propyl)-cyclopentane-1,3-dione, and Allantoin Derived from the Polyherbal Combination of Aristolochia indica L. and Piper nigrum L.

Dhivya Sivaraj | Ray J. Butcher | ... | Karuppusamy Arunachalam
  • Special Issue
  • - Volume 2022
  • - Article ID 4024331
  • - Review Article

Urtica dioica-Derived Phytochemicals for Pharmacological and Therapeutic Applications

Yasaman Taheri | Cristina Quispe | ... | William C. Cho
  • Special Issue
  • - Volume 2022
  • - Article ID 7378807
  • - Research Article

Jianpi Qingchang Decoction Ameliorates Chronic Colitis in Piroxicam-Induced IL-10 Knockout Mice by Inhibiting Endoplasmic Reticulum Stress

Qian Chen | Ya-Li Zhang | ... | Zhi-Peng Tang
  • Special Issue
  • - Volume 2022
  • - Article ID 6098929
  • - Research Article

Gastroprotective Effect of Polypeptide-K Isolated from Momordica charantia’s Seeds on Multiple Experimental Gastric Ulcer Models in Rats

Nurul ’Ain Abu Bakar | Muhammad Nazrul Hakim Abdullah | ... | Yoke Keong Yong
  • Special Issue
  • - Volume 2022
  • - Article ID 5331537
  • - Research Article

The Inhibitory Effects of Naringin in a Rat Model of Postoperative Intraperitoneal Adhesion Formation

Xiaoqiang Shi | Yunhua Wu | ... | Shufeng Wang
Evidence-Based Complementary and Alternative Medicine
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