Evidence-Based Complementary and Alternative Medicine

Ginseng (Panax spp.) in Ethnomedicine and Modern Drug Research


Publishing date
01 Jan 2021
Status
Open
Submission deadline
21 Aug 2020

Lead Editor

1PHENIKAA University, Hanoi, Vietnam

2Nagasaki International University, Nagasaki, Japan

3Vietnam-Korea Institute of Science and Technology (VKIST), Hanoi, Vietnam


Ginseng (Panax spp.) in Ethnomedicine and Modern Drug Research


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Description

Herbal medicines have been used for the treatment of various diseases for thousands of years in Asia and make up a large share in the market in the form of drugs, dietary supplements, and foods. In the West, botanical medicines are categorized as complementary/alternative medicines, dietary supplements, or foods. Many modern drugs come from natural sources, including medicinal plants.

The Panax genus belonging to Araliaceae family includes 12 species, which are distributed in Asia and North America. Many Panax species have been used for medicinal purposes, especially in Eastern Asian traditional medicine, as a valuable tonic and for the treatment of certain diseases. The typical and most well-known Panax species include Korean ginseng/Asian ginseng (Panax ginseng), American ginseng (P. quiquefolius), Sanchi ginseng (P. notoginseng), Japanese ginseng (P. japonicus) and Vietnamese ginseng (P. vietnamensis). These species are known for their therapeutic potential, large-scale cultivation and various health products. Phytochemical profiles of Panax species have been extensively investigated and, to date, more 300 saponins/ginsenosides have been documented and classified into the two groups of dammarane-type and oleanane-type. While P. ginseng, P. quinquefolius, P. vietnamensis, P. notoginseng are well documented to contain mainly dammarane-type saponins, oleanane-type saponins are predominant in P. bipinnatifidus, and P. stipuleanatus. P. japonicus comprise of a variety of saponins in both dammarane and oleanane-type skeletons. Some ginsenosides have become leading compounds in modern drug development, and ginsenoside Rg3 has recently been approved and marketed in China as an API in an anti-cancer drug. Therefore, ginseng saponins/ginsenosides have been found to be promising resources in the development of new drugs.

This Special Issue aims to curate research from interdisciplinary pharmaceutical sciences including chemistry of natural products from ginseng, biological and pharmacological activities of ginseng and ginseng products, and biotechnology in ginseng research for the promotion of ginseng in medicinal purposes, especially in modern drug development. We welcome both original research articles and reviews that contribute to ginseng research, deepening understanding of the scientific background and potential of ginseng and its components in modern medicine.

Potential topics include but are not limited to the following:

  • Chemistry of natural products from ginseng: structure (isolation, structural optimisation, semi-synthesis and total synthesis), qualitative/quantitative analyses and standardisation, and chemotaxonomy
  • Evaluation of the biological and pharmacological effects of ginseng and ginseng products (in silico, in vitro, and in vivo)
  • Biotechnology in ginseng research
  • Searching for new and/or alternative resources of ginseng and ginseng products
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate26%
Submission to final decision67 days
Acceptance to publication33 days
CiteScore2.900
Impact Factor1.813

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