Evidence-Based Complementary and Alternative Medicine

GAP: From Sound Design to Practical Implementation in Clinical Trials for Traditional Chinese Medicine


Publishing date
20 Dec 2013
Status
Published
Submission deadline
02 Aug 2013

1Tianjin University of TCM, Tianjin, China

2China Academy of Chinese Medical Sciences, Beijing, China

3School of Chinese Medicine, Hong Kong Baptist University, Hong Kong

4Chinese Cochrane Centre, Chinese Evidence-Based Medicine Centre, Chengdu, China

5All Ireland Hub for Trials Methodology Research, UK

6University of Southbank, London, UK


GAP: From Sound Design to Practical Implementation in Clinical Trials for Traditional Chinese Medicine

Description

Research design, implementation, and process evaluation are steps of critical importance for clinical studies with traditional Chinese medicine (TCM).The years following 1980s witnessed the introduction of clinical epidemiology, evidence-based medicine (EBM), and good clinical practice (GCP) into domestic academia, and since then there has been a growing acceptance and application of the concepts, models, and tools developed in the above areas in clinical studies for TCM. A number of scholars believed that the use of scientific methodology can improve the rigor of clinical studies in the area of TCM and therefore devoted themselves to promoting it in practice. Randomized controlled trials (RCTs), cohort studies, and case-control studies have greatly increased in clinical research with TCM, and instead of favoring RCTs they had a rationale to justify their choice of a particular study design. However, having a sound design is just the first step towards research success. How to overcome obstacles to practical implementation of clinical trials posed another major challenge to trial managers and investigators. A widening gap has been observed between the methodologists’ preference for an “innovative” yet impracticable design and the researchers’ emphasis on needs and real circumstances of the patients and clinical practice. This led to departures from requirements stipulated in the study protocol and endangered the success of many clinical studies. In view of this, we have planned a special issue that can provide guidance on bridging the gap.

We invite investigators to contribute original research articles as well as review articles that focus on sound design and practical implementation in clinical studies with TCM. The information obtained from these studies shall be clearly evidence-based. Potential topics include, but are not limited to:

  • The practicability of study designs in clinical research of TCM
  • The need for unblinded clinicians to administer certain treatments
  • Comparisons between different types of therapies, for example, acupuncture against a medication
  • Factors influencing quality control in clinical research of TCM
  • Compliance control in clinical research of TCM
  • Methodology for process assessment in clinical research of TCM
  • Global lessons on keeping the balance between a scientific design and practicability in implementation
  • Experiences with and lessons learned from past clinical studies with TCM

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/ecam/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ecam/gap/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 560838
  • - Editorial

GAP: From Sound Design to Practical Implementation in Clinical Trials for Traditional Chinese Medicine

Hongcai Shang | Boli Zhang | ... | Nicola Robinson
  • Special Issue
  • - Volume 2014
  • - Article ID 605714
  • - Research Article

Chinese Medicine Shensongyangxin Is Effective for Patients with Bradycardia: Results of a Randomized, Double-Blind, Placebo-Controlled Multicenter Trial

Yunfang Liu | Ning Li | ... | Jielin Pu
  • Special Issue
  • - Volume 2014
  • - Article ID 376058
  • - Review Article

Improving Participant Adherence in Clinical Research of Traditional Chinese Medicine

Wenke Zheng | Bai Chang | Jing Chen
  • Special Issue
  • - Volume 2013
  • - Article ID 245958
  • - Review Article

The Effects of Wenxin Keli on P-Wave Dispersion and Maintenance of Sinus Rhythm in Patients with Paroxysmal Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials

Yu Chen | Shaoping Nie | ... | Hongcai Shang
  • Special Issue
  • - Volume 2013
  • - Article ID 847273
  • - Research Article

Understanding Patient Values and the Manifestations in Clinical Research with Traditional Chinese Medicine—With Practical Suggestions for Trial Design and Implementation

Wei Mu | Hongcai Shang
  • Special Issue
  • - Volume 2013
  • - Article ID 541217
  • - Research Article

Clinical Study on the Prevention of Oxaliplatin-Induced Neurotoxicity with Guilongtongluofang: Results of a Randomized, Double-Blind, Placebo-Controlled Trial

Yunfang Liu | Guangying Zhu | ... | Huiming Yu
  • Special Issue
  • - Volume 2013
  • - Article ID 202703
  • - Review Article

Clinical Research of Traditional Chinese Medicine Needs to Develop Its Own System of Core Outcome Sets

Li Zhang | Junhua Zhang | ... | Hongcai Shang
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate26%
Submission to final decision70 days
Acceptance to publication39 days
CiteScore2.010
Impact Factor1.984
 Submit

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.