Evidence-Based Complementary and Alternative Medicine

Acupuncture and Oxidative Stress


Publishing date
07 Nov 2014
Status
Published
Submission deadline
20 Jun 2014

Lead Editor

1Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China

2Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA

3Department of Surgery, LABCEX, UFC, Ceara, Brazil

4Capital Medical University, Beijing, China


Acupuncture and Oxidative Stress

Description

As one of the modalities of traditional Oriental medicine, acupuncture has been widely used to treat many disorders and diseases, including chronic pain, stroke, and insomnia as well as depression, while its mechanisms remain unclear. Recent experimental studies have demonstrated that acupuncture can attenuate oxidative stress in different diseases, which also need quite a lot of efforts to deeply understand although a few progresses have been made.

Reactive oxygen species, including superoxide anion (O2-), hydrogen peroxide (H2O2), hydroxyl radical (OH-), are generated during stroke, Alzheimer's disease, Parkinson's disease, diabetes mellitus, and so on. Under normal physiological circumstances, there is a balance between antioxidants and oxidants produced by aerobic cellular systems. Enhanced production of reactive oxygen species (ROS) causes oxidative stress leading to damage in lipids, proteins, and nucleic acids. Previous studies proved that acupuncture exerts therapeutical effect by modulating oxidative stress biomarkers such as 8-hydroxy-2'-deoxyguanosine (8-OHdG), antioxidative enzymes including superoxide dismutase (SOD), prooxidants such as ROS, and reactive nitrogen species (RNS). Since redox reaction is associated with oxidative stress state, it is plausible that the dynamic equilibrium of oxidation and reduction could be used to evaluate the antioxidative effects of acupuncture in some diseases. Furthermore, studies using oxidative stress-related assessments techniques and the specific oxidative stress biomarkers should be particularly useful in generating new hypotheses to better our understanding of the mechanism of antioxidative effects of acupuncture.

We invite investigators to contribute original research articles as well as review articles that will stimulate continuing efforts to understand the physiological mechanisms of antioxidative effect of acupuncture. Potential topics include, but are not limited to:

  • Effects of acupuncture on biological markers of oxidative stress
  • Effects of acupuncture on antioxidative enzymes and nonenzymes
  • Effect of acupuncture on the oxidative stress in health and diseases
  • Effects of acupuncture on redox signaling pathways
  • The assessments techniques of antioxidative effect of acupuncture
  • Mechanisms by which acupuncture plays a role in oxidative stress
  • Interaction of acupuncture and medicines on antioxidative effect
  • Recent advances in acupuncture and oxidative stress research

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/ecam/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ecam/aost/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 424762
  • - Editorial

Acupuncture and Oxidative Stress

Cun-Zhi Liu | Shu-Feng Zhou | ... | Guang-Xia Shi
  • Special Issue
  • - Volume 2015
  • - Article ID 286989
  • - Research Article

Monitoring the Effects of Acupoint Antioxidant Intervention by Measuring Electrical Potential Difference along the Meridian

Ming-Ming Xu | Jing-Ke Guo | ... | Ping-Fan Rao
  • Special Issue
  • - Volume 2015
  • - Article ID 204367
  • - Research Article

MicroRNA Profiling Response to Acupuncture Therapy in Spontaneously Hypertensive Rats

Jia-You Wang | Hui Li | ... | Shu-Feng Zhou
  • Special Issue
  • - Volume 2014
  • - Article ID 937601
  • - Research Article

Laser Acupuncture at HT7 Acupoint Improves Cognitive Deficit, Neuronal Loss, Oxidative Stress, and Functions of Cholinergic and Dopaminergic Systems in Animal Model of Parkinson’s Disease

Jintanaporn Wattanathorn | Chatchada Sutalangka
  • Special Issue
  • - Volume 2014
  • - Article ID 483294
  • - Review Article

Acupuncture Mechanism and Redox Equilibrium

Xiang-Hong Zeng | Qian-Qian Li | ... | Cun-Zhi Liu
  • Special Issue
  • - Volume 2014
  • - Article ID 253075
  • - Research Article

ERK1/2-Egr-1 Signaling Pathway-Mediated Protective Effects of Electroacupuncture in a Mouse Model of Myocardial Ischemia-Reperfusion

Juan Zhang | Jiangang Song | ... | Xiangrui Wang
  • Special Issue
  • - Volume 2014
  • - Article ID 943596
  • - Research Article

Electroacupuncture Ameliorates Acute Lung Injury through Promoting Gastrointestinal Motility in Rats with Acute Pancreatitis

Hui Guo | Shi-Feng Zhu | ... | Wen-Fu Tang
  • Special Issue
  • - Volume 2014
  • - Article ID 495379
  • - Research Article

Acupuncture Relieves the Excessive Excitation of Hypothalamic-Pituitary-Adrenal Cortex Axis Function and Correlates with the Regulatory Mechanism of GR, CRH, and ACTHR

Shao-Jun Wang | Jiao-Jiao Zhang | Li-Li Qie
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate28%
Submission to final decision80 days
Acceptance to publication46 days
CiteScore2.010
Impact Factor1.984
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