Potential of Terpenoids and Flavonoids from Asteraceae as Anti-Inflammatory, Antitumor, and Antiparasitic Agents
1Universidad de Buenos Aires, Buenos Aires, Argentina
2National University of Tucumán, Tucumán, Argentina
3Academy of Sciences, Tashkent, Uzbekistan
4Federal University of Sao Paulo, Sao Paulo, Brazil
Potential of Terpenoids and Flavonoids from Asteraceae as Anti-Inflammatory, Antitumor, and Antiparasitic Agents
Description
Asteraceae, also known as Compositae, is one of the largest families and it is widely distributed in the world. It comprises more than 1700 genera with over 23000 species. In the last decades, different species from this family have been studied because of the variety and amount of bioactive compounds in it. Among them, terpenoids and flavonoids stand out because of their biological activities being anti-inflammatory, antitumor, and antiparasitic the most relevant. Many of these bioactive compounds or their derivatives are used in therapy or are in preclinical or clinical trials. The flavonoid quercetin is in clinical trials for prostate cancer and its primary prevention. Within terpenoids, the sesquiterpene lactones artemisinin and arglabin, both isolated from Artemisia species, are approved drugs for human malaria and cancer treatment, respectively.
In this sense, the aim of this special issue is to publish research papers as well as review articles addressing recent advances on the study of terpenoids and flavonoids from Asteraceae as potential anti-inflammatory, antitumor, and antiparasitic agents. Original high quality contributions that are not yet published or that are not currently under review by other journals are expected. Papers concerning extraction and biological activities of essential oils will not be considered.
Potential topics include but are not limited to the following:
- Isolation and identification of bioactive terpenoids and/or flavonoids from Asteraceae
- Anti-inflammatory, cytotoxic, and/or antiparasitic activity of previously isolated terpenoids and/or flavonoids
- Semisynthetic derivatives of natural bioactive terpenoids and/or flavonoids
- Mechanism of action of bioactive terpenoids and/or flavonoids