Research Article

New Insights into the Role of Metformin Effects on Serum Omentin-1 Levels in Acute Myocardial Infarction: Cross-Sectional Study

Table 3

Biochemical changes and serum omentin-1 levels in acute MI in the patients that were not previously treated with metformin prior to acute MI in comparison with normal healthy control subjects.

Biochemical parametersGroup III ()
Mean ± SD
Group II ()
Mean ± SD
95% CI
Upper-lower limits
p

S. omentin-1 pg/mL27.13 ± 1.5523.71 ± 1.16112.085227.7088–26.5512<0.0001
S. troponin-I pg/mL21.202 ± 2.63679.53 ± 3.60−121.19722.1863–20.2177<0.0001
FBG mg/dL118.96 ± 9.704138.77 ± 17.467−11.181122.5835–115.3365<0.0001
Total cholesterol mg/dL140.96 ± 30.091242.44 ± 12.552−18.4716152.1962–129.7238<0.0001
TG mg/dL138.66 ± 10.366246.55 ± 57.607−57.007142.530–134.7893<0.0001
HDL-C mg/dL51.23 ± 5.88238.77 ± 4.57011.602653.4264–49.0336<0.0001
VLDL-C mg/dL27.64 ± 2.08249.30 ± 11.524−56.982128.4174–26.8626<0.0001
LDL-C mg/dL62.08 ± 3.834154.37 ± 4.316−722.13362.3414–61.8186<0.0001
AI0.072 ± 0.0080.443 ± 0.0084−254.0060.075–0.069<0.0001
SPB mmHg123.16 ± 9.042162.33 ± 10.61−23.727126.5363–119.7837<0.0001
DPB mmHg75.50 ± 11.643105.16 ± 21.784−13.95379.8476–71.1524<0.0001

Group II: patients have not received metformin prior to acute MI. Group III: normal healthy controls have not received any drugs.
. FBG: fasting blood glucose, TG: triglyceride, HDL: high density lipoprotein, VLDL: very low density lipoprotein, LDL: low density lipoprotein, AI: atherogenic index, SPB: systolic blood pressure, and DPB: diastolic blood pressure.