Research Article

New Insights into the Role of Metformin Effects on Serum Omentin-1 Levels in Acute Myocardial Infarction: Cross-Sectional Study

Table 4

Biochemical changes and serum omentin-1 level in acute MI in the patients that were not previously treated with metformin prior to acute MI in comparison with the patients previously treated with metformin.

Biochemical parametersGroup I ()
Mean ± SD
Group II ()
Mean ± SD
95% CI
Upper-lower limits
p

S. omentin-1 pg/mL25.43 ± 1.223.71 ± 1.16111.286125.7347–25.1253<0.0001
S. troponin-I pg/mL75.453 ± 5.6279.53 ± 3.60−5.712276.8802–74.0258<0.0001
FBG mg/dL137.75 ± 13.139138.77 ± 17.467−0.6113141.0867–134.41330.5433
Total cholesterol mg/dL152.63 ± 16.877242.44 ± 12.552−41.9011156.916–148.344<0.0001
TG mg/dL149.34 ± 23.31246.55 ± 57.607−32.8371155.2596–143.4204<0.0001
HDL-C mg/dL54.24 ± 8.35538.77 ± 4.57014.579456.3618–52.1182<0.0001
VLDL-C mg/dL29.86 ± 4.66249.30 ± 11.524−32.833731.0439–28.6761<0.0001
LDL-C mg/dL68.13 ± 3.937154.37 ± 4.316−13581.0868.1427–68.1173<0.0001
AI0.082 ± 0.090.443 ± 0.084−31.58350.1049–0.0591<0.0001
SPB mmHg140.33 ± 8.773162.33 ± 10.61−19.745142.5579–138.1021<0.0001
DPB mmHg82.16 ± 8.773105.16 ± 21.784−20.643184.3879–79.9321<0.0001

Group I: patients received metformin prior to acute MI. Group II: patients have not received metformin prior to acute MI.
. FBG: fasting blood glucose, TG: triglyceride, HDL: high density lipoprotein, VLDL: very low density lipoprotein, LDL: low density lipoprotein, AI: atherogenic index, SPB: systolic blood pressure, and DPB: diastolic blood pressure.