Prognostic Value of Serum Albumin at Admission for Neurologic Outcome with Targeted Temperature Management after Cardiac Arrest

Table 1

Baseline characteristics between patients with and without admission hypoalbuminemia.

	Hypoalbuminemia (<3.5 g/dl, n = 109)	Normal serum albumin (≥3.5 g/dl, n = 146)
Demographics
Male	76 (69.7)	104 (71.2)	0.794
Age, years	61.7 ± 15.9	49.5 ± 15.3	<0.001
Comorbidities
CAD	12 (11.0)	19 (13.0)	0.628
CHF	2 (1.8)	6 (4.1)	0.472
Stroke	3 (2.8)	2 (1.4)	0.654
Hypertension	40 (36.7)	36 (24.7)	0.038
Diabetes mellitus	36 (33.0)	19 (13.0)	<0.001
Renal disease	14 (12.8)	3 (2.1)	0.001
Liver disease	2 (1.8)	0 (0.0)	0.182
Malignancy	7 (6.4)	4 (2.7)	0.213
Resuscitation variables
Cardiac cause	71 (65.1)	104 (71.2)	0.299
Shockable rhythm	23 (21.1)	75 (51.4)	<0.001
Witnessed	75 (68.8)	107 (73.8)	0.383
Bystander CPR	56 (51.4)	86 (59.3)	0.207
Anoxic time (min)	37.4 ± 18.3	30.9 ± 20.7	0.009
Post-ROSC N/Ex
PLR	26 (23.9)	69 (47.3)	<0.001
Self-respiration	41 (37.6)	90 (61.6)	<0.001
GCS motor, yes	14 (12.8)	46 (31.5)	<0.001
Hemodynamic status
MAP	83.9 ± 26.9	97.1 ± 25.5	<0.001
HR	100.9 ± 28.3	105.0 ± 26.9	0.234
Temperature	35.3 ± 1.6	35.8 ± 1.0	0.005
Outcomes
Pneumonia	56 (51.4)	53 (36.3)	0.016
Septic shock	10 (9.2)	16 (11.0)	0.641
HD (days)	7.0 (3.0–20.0)	12.0 (6.0–20.0)	0.005
6-month mortality	90 (82.6)	59 (40.4)	<0.001
6-month poor neurologic outcome	95 (87.2)	76 (52.1)	<0.001

CAD, coronary artery disease; CHF, congestive heart failure.