Research Article

The Effect of a Modified Constant Flow Insufflation of Oxygen during Cardiopulmonary Resuscitation in a Rat Model of Respiratory Cardiac Arrest on Arterial Oxygenation, Alveolar Barotrauma, and Brain Tissue Injury

Table 2

Baseline characteristics of the experimental rats, all of which were male and approximately 15 weeks old.

Sham (n = 10)Group IPPV (n = 10)Group CFIO (n = 10) value
Age15 weeks old
SexMale

Weight, g419.00 (415.75–421.00)417.50 (413.25–421.25)418.00 (414.50–421.25)0.86
Arrest induction time, sNA499.50 (491.25–510.00)500.00 (495.75–508.00)0.66
pH7.32 (7.29–7.34)7.33 (7.31–7.35)7.32 (7.29–7.34)0.79
PCO232.00 (30.25–33.78)31.55 (30.25–34.43)30.15 (29.63–32.13)0.19
PO2121.15 (119.18–125.45)121.70 (116.85–127.68)120.65 (118.95–125.65)0.98
HCO3-30.10 (29.33–30.90)29.65 (28.98–30.23)29.10 (28.60–29.65)0.31
Base excess−1.55 (−1.8–−1.2)−1.3 (−1.93–1.08)−.3 (−1.43–−1.18)0.67
Lactate2.00 (1.78–2.10)2.10 (2.00–2.30)2.05 (1.98–2.13)0.31

Kruskal-Wallis analysis, median (IQR), was considered statistically significant. IPPV, intermittent positive pressure ventilation; CFIO, continuous flow insufflation of oxygen; NA, not applicable.