Research Article
The Effect of Mesenchymal Stromal Cells on the Mortality of Patients with Sepsis and Septic Shock: A Promising Therapy
Table 3
Cytokine levels and laboratory results of the patients in the ADMSC group.
| | | Treatment days | | | 0 | 1 | 3 | 5 | 7 |
| | Cytokines | | IL-2 | 42.1 (28.5–304.9) | 76.0 (25.2–279.3) | 71.8 (40.0–273.6) | 59.0 (15.4–243.4) | 59.3 (45.0–258.0) | 0.516 | | IL-4 | 418.4 (4.3–2597.5) | 298.8 (0.9–2639.8) | 210.0 (54.2–2390.8) | 280.8 (24.6–2602.5) | 417.5 (25.4–2716.7) | 0.404 | | IL-10 | 18.5 (0.4–81.7) | 19.2 (9.6–84.3) | 15.9 (0.9–79.9) | 13.8 (8.2–83.0) | 13.4 (7.5–89.9) | 0.647 | | TNF-α | 105.5 (35.2–557.7) | 136.5 (68.7–564.8) | 140.6 (59.1–549.5) | 123.7 (59.1–612.7) | 99.0 (8.7–545.4) | 0.416 | | IF-Ɣ | 150.1 (82.2–814.6) | 166.0 (101.9–956.7) | 169.9 (109.5–953.7) | 172.2 (73.7–1029.4) | 181.4 (85.5–992.5) | 0.275 | | Laboratory results | | CRP (mg/mL) | 207 (32–334) | 129 (99–279) | 96 (46–217) | 82 (20–275) | 75 (17–208) | 0.028 | | PCT (mg/mL) | 3.6 (0.7–100.0) | 3.1 (1.2–50.0) | 2.8 (1.3–10.0) | 2.2 (0.5–100.0) | 1.6 (0.5–56.0) | 0.641 | | WBC (µ/L) | 17100 (3070–41800) | 14840 (2750–39470) | 12715 (2820–46570) | 11190 (1990–40310) | 11440 (2210–36940) | 0.045 | | Lactate (mmol/L) | 1.43 (0.82–3.17) | 1.40 (1.09–2.20) | 1.33 (0.99–2.29) | 1.30 (0.63–2.84) | 1.30 (0.80–4.84) | 0.170 | | SOFA score (adjusted) | 3.02 ± 0.84 | 2.7 ± 0.83 | 2.48 ± 0.75 | 1.99 ± 1.08 | 2.2 ± 0.78 | 0.027 adjusted |
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