Review Article

Phospholipases A in Trypanosomatids

Figure 2

Multiple sequence alignment of trypanosome PLA1. Alignment of the protein sequences of cloned T. brucei, T. cruzi, and L. braziliensis PLA1 and T. congolense and T. vivax putatives PLA1 was performed with NTI 10 Software (Invitrogen) using the Clustal W algorithm. The lipase consensus pattern is underlined. Letters indicate: identical (red), conserved (blue), similar (green), weakly similar (grey), and nonsimilar (black) amino acids. Leishmania braziliensis PLA1 (TriTrypDB LbrM31_V2.2750), Trypanosoma brucei PLA1 (TriTrypDB Tb.927.1.4830), Trypanosoma congolense putative PLA1 (TriTrypDB TcIL3000.1.2010), Trypanosoma vivax putative PLA1 (TriTrypDB TvY486_0102170), and Trypanosoma cruzi PLA1 (TriTrypDB Tc00.1047053510679.100).
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