Trypanosome Prereplication Machinery: A Potential New Target for an Old Problem
Figure 4
(a) Shows the archaea Orc1/Cdc6 structure together with ATP. The AAA+ and WH domains are indicated. (b) Shows the predicted structure of T. cruzi Orc1/Cdc6, obtained using the 3D-PSSM program (http://www.sbg.bio.ic.ac.uk/~3dpssm/index2.html).