The Sphingolipid Biosynthetic Pathway Is a Potential Target for Chemotherapy against Chagas Disease

<table>Lipid remodeling pathways in mammals, yeast and <i>T. cruzi</i>. “R” represents the entire glycan structure of each GPI anchor precursor linked to a protein. Although this assumption has been validated in mammals (top panel) and yeast (middle panel), no such experimental data are available for <i>T. cruzi</i> (bottom panel). Each step (in parentheses) has corresponding entries in Table <a href="../tab1/">1</a>.</table>

Enzyme Research

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Figure 2: The Sphingolipid Biosynthetic Pathway Is a Potential Target for Chemotherapy against Chagas Disease 