Research Article

Molecular Cloning and Characterization of P4 Nuclease from Leishmania infantum

Table 1

Similarity of predicted amino acid sequence of Li-P4 nuclease with different promastigote-specific P1/S1 nuclease of various Leishmania species.

Leishmania speciesIdentity %*Positivity %**

P4 nuclease (Leishmania infantum)100100
P1/S1 secretary nuclease (Leishmania donovani)8992
p1/s1 nuclease (Leishmania major)8189
single strand-specific nuclease (Leishmania pifanoi)7785
P4 nuclease (Leishmania amazonensis)7585

*Identity is referred to the extent to which two sequences are invariant.
**Positivity is referred to the extent to which two sequences possess amino acids with the same physicochemical properties.