Table of Contents
Epidemiology Research International
Volume 2012 (2012), Article ID 153539, 6 pages
Research Article

Resting and Dynamic Electrocardiography in Dogs with Experimental Chagas Cardiomyopathy

1Departamento de Medicina Veterinária, Universidade Federal de Goiás, Goiânia, GO, Brazil
2Departamento de Medicina e Cirurgia Veterinárias, UNESP, Jaboticabal, SP, Brazil

Received 21 March 2012; Revised 8 May 2012; Accepted 10 May 2012

Academic Editor: Alfonso J. Rodriguez-Morales

Copyright © 2012 R. Oliveira Alves et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In the present protocol, adult dogs were infected with Trypanosoma cruzi, Bolivian strain, in order to show electrocardiographic changes by means of resting and dynamic (Holter) methods during acute and chronic phases of Chagas disease. In the acute phase there were sinus tachycardia, atrial and left ventricular overload, millivoltage suppression, electric alternance, and episodes of sinus arrest. At the parasitemia peak, atrium-ventricular block, junctional escape complexes, and atrium-ventricular dissociation were observed. Dogs that presented the most serious arrhythmias died suddenly. The increase in supraventricular and ventricular arrhythmic events, concentrated in the 4th postinoculation week, was visible at electrocardiographic monitoring. In the chronic phase, the events were restricted to first-degree atrium-ventricular blocks, premature ventricular complexes, ventricular bigeminy, and electrical alternation. It was concluded that the computerized and dynamic electrocardiography allowed to diagnose transient arrhythmia and to observe that the main tachyarrhythmic changes are concentrated at the acute phase concomitantly to the parasitemia peak.