Table of Contents
Epilepsy Research and Treatment
Volume 2010, Article ID 725696, 10 pages
http://dx.doi.org/10.1155/2010/725696
Review Article

Evolution and Prospects for Intracranial Pharmacotherapy for Refractory Epilepsies: The Subdural Hybrid Neuroprosthesis

Comprehensive Epilepsy Center, New York University School of Medicine, NYU Langone Medical Center, 223 East 34th Street, New York, NY 10016, USA

Received 11 September 2009; Accepted 5 November 2009

Academic Editor: Annamaria Vezzani

Copyright © 2010 Nandor Ludvig et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

This movie clip shows:

  • Focal EEG seizure in the right frontal cortex pre-treated with artificial CSF (ACSF)

  • The “switch-on” electrical artifact by the minipump on the rat's head

  • The termination of the ongoing EEG seizure about 10 sec after the epidural delivery of 1.0 mM 50 (μl) muscimol with this minipump

  1. Supplementary Material
  2. Supplementary Material