Research Article

Hippocampography Guides Consistent Mesial Resections in Neocortical Temporal Lobe Epilepsy

Table 2

Group characteristics.

Mesial ECoG
(EHG-guided hippocampectomy)
Lateral ECoG
(unguided hippocampectomy)
Group differences 
p (univariate)
Association with Engel I 
p (univariate)

Primary outcome
 Hippocampectomy variability (deviation from mean, cm)0.7 (0.2–2.3)1.8 (0.6–4.9)0.01n/a
Secondary outcomes
 Absolute hippocampectomy length (cm)2.2 (1–4.5)3.1 (0.5–8)0.200.74
 Engel Class I12 (86%)5 (42%)0.02n/a
Possible confounders of secondary outcome Engel Class I
 Age31.8 (7–66)37.8 (18–74)0.360.64
 Male gender8 (57%)6 (50%)0.720.48
 Comorbid MTS6 (43%)6 (50%)0.720.34
 NTLE+M7 (50%)1 (8%)0.0510.02
 NTLE+E1 (7%)3 (25%)0.070.96
 NTLE+M+E1 (7%)5 (42%)0.0020.046
 Follow-up duration1.7 (0.03–4.22)2.1 (0.03–4.63)0.400.07

Statistically significant on univariate analysis.
Statistically significant on multivariate analysis: NTLE+M was positively associated with Engel I; NTLE+M+E was negatively associated against Engel I.
NTLE+M: neocortical temporal lobe epileptogenic lesion with mesial temporal invasion; NTLE+E: neocortical temporal lobe epileptogenic lesion with extratemporal invasion; NTLE+M+E: neocortical temporal lobe epileptogenic lesion with mesial temporal and extratemporal invasion; n/a: not applicable.