Safety, Tolerability, Pharmacokinetics, and Efficacy of Terlipressin Delivered by Continuous Intravenous Infusion in Patients with Cirrhosis and Refractory Ascites

Table 3

Summary of terlipressin PK parameters.

	CL (L/min)	CL (mL/min/kg)	V (L)	V (L/kg)	K (min^-1)	(min)
Mean	0.49	5.6	31.6	0.33	0.020	42.3
Median	0.49	5.7	23.5	0.29	0.019	37.1
%CV	24.2	16.7	80.2	53.2	49.2	52.1
Range	0.34, 0.69	4.1, 6.9	13.8, 82.3	0.18, 0.68	0.008, 0.038	18.3, 83.1

CL: clearance; %CV: percent coefficient of variation; K: elimination rate constant; : half-life; V: volume of distribution.