The Identification of Childhood Asthma Progression-Related lncRNAs and mRNAs Suitable as Biomarkers Using Weighted Gene Coexpression Network Analysis

Figure 1

Identification of differentially expressed RNAs (DERs) and functional analyses of overlapped differentially expressed mRNAs (DE-mRNAs). (a) The volcano figures of DERs. Left: the volcano figure of DERs in the GSE19187 dataset. Right: the volcano figure of DERs in the GSE65204 dataset. Green and red dots represent downregulated and upregulated DERs, respectively. The horizontal dotted line represents the value of the false discovery rate <0.05; the vertical dotted line represents the value of the |log₂ fold change (FC)| > 0.5. (b) Venn diagram of DERs found in the GSE19187 and GSE65204 datasets and DERs common between them. (c) Biological processes (BPs) significantly associated with overlapped DE-mRNAs. (d) The overlapped DE-mRNAs significantly enriched in Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.

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