The Underlying Molecular Basis and Mechanisms of Venous Thrombosis in Patients with Osteomyelitis: A Data-Driven Analysis

Table 2

The list of TF-target gene pairs of VTEGs2 and OMGs2.

Shared TFs	VTEGs2				OMGs2
	No.	Target genes	value	Q value	No.	Target genes	value	Q value
E2F1	2	TP53, NRIP1	0.483	0.497	5	CDKN1C, PPARG, RRM2, IL23A, PCSK6	0.0863	0.124
GATA1	4	MPL, DICER1, HBE1, GYPB	0.005	0.0245	3	PRG2, ALAS2, FCER1A	0.0778	0.115
JUN	3	CSTA, NAMPT, TP53	0.269	0.312	3	IL23A, CTGF, PLAU	0.485	0.496
NFKB1	5	CD3G, NAMPT, BCL2A1, ICAM1, TP53	0.304	0.332	12	PTGES, TFF3, COL1A2, SOCS3, PLAU, HOXA9, CR2, HPSE, CD86, IL4, OLFM4, IL23A	0.00727	0.0347
RELA	5	BCL2A1, TRIB3, ICAM1, NAMPT, TP53	0.299	0.332	11	TFF3, COL1A2, IL4, IL23A, CD86, PTGES, PLAU, OLFM4, HPSE, CR2, SOCS3	0.0172	0.0674
RUNX1	2	PIK3CD, MPL	0.0841	0.121	3	MPO, ELANE, BPI	0.0325	0.0874
SIRT1	3	HBE1, ICAM1, TP53	0.0202	0.0519	2	PPARG, COL1A2	0.205	0.242
SP1	9	CYP1B1, ICAM1, LSP1, FBLN1, CD151, ATP2A3, MCTS1, DCK, FOS	0.119	0.153	9	MMRN1, MPO, LSP1, MME, CTGF, ITGB3, PLAU, PTGES, LTF	0.443	0.464
SPI1	3	FCGR1A, ACP5, BCL6	0.0391	0.0741	8	FCER1A, ELANE, BPI, P2RY10, CTSG, FCGR1A, PRG2, MME	1.19E-05	0.000512
STAT1	3	TP53, ICAM1, FCGR1A	0.0815	0.121	4	CD86, FCGR1A, IL1R1, SOCS3	0.0597	0.112
STAT3	4	FOS, ICAM1, BCL6, TP53	0.0936	0.13	4	PROS1, CTGF, HP, SOCS3	0.237	0.262
TP53	2	TP53, PMAIP1	0.592	0.592	3	PAX5, NLRC4, VCAN	0.549	0.549
YY1	3	TP53, COX7C, HBE1	0.0979	0.131	4	COL1A2, DNAJB4, FCER1A, IL4	0.0754	0.115