Genetics Research International / 2011 / Article / Tab 1

Research Article

Autosomal Recessive Nonsyndromic Hearing Impairment due to a Novel Deletion in the RDX Gene

Table 1

Two-point and multipoint LOD scores for family 4208 at chromosome 11q22.3-q24.1.

Marker name1Physical map position2Genetic map position3Multipoint LOD scoreTwo-point LOD score at θ =
0.00.010.050.100.200.30

D11S237173,182,77884.41−∞−∞−0.350.240.370.310.15
D11S200279,643,05091.48−13.66−∞−1.41−0.180.200.330.22
D11S2000105,063,887111.71−6.18−6.08−0.150.901.070.830.42
D11S1391110,200,327115.145.203.183.102.742.291.430.68
D11S1998117,202,969126.245.784.474.363.953.412.331.26
D11S4464123,131,592136.99−∞−∞−2.84−0.93−0.250.160.17
D11S912128,129,301145.13−∞−∞−1.52−0.62−0.250.010.06
D11S968133,323,584160.10−4.03−1.95−0.060.540.640.450.18

1Markers in bold denote marker limits based on the 3-unit support interval and the homozygous region.
2Physical map positions in base pairs from Build 36 of the human reference sequence.
3Genetic map positions in cM from Rutgers combined linkage-physical map of the human genome Build 36 version.

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