A Novel ESRRB Deletion Is a Rare Cause of Autosomal Recessive Nonsyndromic Hearing Impairment among Pakistani Families

Table 1

Two-point and multipoint LOD scores for family 4243.

Marker name^1	Physical map position^2	Genetic map position^3	Multipoint LOD score	Two-point LOD score at 𝜃 =
				0.00	0.01	0.05	0.10	0.20	0.30
rs221924	70,650,531	66.96	−4.52	−2.02	−0.26	0.28	0.39	0.33	0.20
rs917284	71,806,864	67.80	−2.56	−1.41	0.34	0.84	0.90	0.70	0.36
rs1468507	73,641,851	70.09	4.15	2.67	2.62	2.40	2.12	1.54	0.94
rs935340	75,660,959	72.79	4.16	3.04	2.98	2.72	2.40	1.73	1.06
rs888412	77,676,577	75.73	4.16	1.34	1.30	1.13	0.91	0.46	0.02
rs2043585	79,039,998	77.88	−17.85	−∞	0.58	1.08	1.13	0.92	0.56
rs1530771	80,095,275	78.71	−∞	−∞	0.47	0.98	1.04	0.84	0.50
rs799032	81,707,098	79.67	−∞	−∞	0.84	1.32	1.35	1.09	0.69
rs1964413	82,338,459	80.75	−1.27	2.08	2.04	1.88	1.66	1.22	0.76
rs1885316	84,924,908	82.25	−6.89	−2.37	−0.60	−0.03	0.12	0.15	0.09
rs1956411	88,204,113	85.49	−5.94	−2.10	−0.33	0.22	0.36	0.34	0.22

¹ Markers in bold denote marker limits based on 3-unit support interval and homozygous region.
² Physical map positions from Build 36.1 of human reference sequence.
³ Genetic map positions based on Rutgers linkage physical map of the human genome.